Active Recombinant Mouse Ager Protein, Fc Chimera
Cat.No. : | Ager-958M |
Product Overview : | Recombinant Mouse Ager (Accession # O35444), fused with , was produced in Mouse myeloma cell line, NS0-derived. |
- Specification
- Gene Information
- Related Products
Source : | Mammalian cells |
Species : | Mouse |
Tag : | Fc |
Predicted N Terminal : | No results obtained: Gln24 predicted |
Form : | Lyophilized from a 0.2 µm filtered solution in PBS. |
Bio-activity : | Measured by its binding ability in a functional ELISA.rmRAGE/Fc Chimera immobilized at 5 µg/mL (100 µL/well) on a goat anti-human IgG Fc antibody-coated plate (0.5 µg/well) can bind biotinylated advanced glycation endproducts of bovine serum albumin (AGE-BSA) with a linear range of 0.02 - 1 µg/mL. |
Molecular Mass : | Recombinant Mouse Ager, Fc Chimera has a calculated MW of 60.5 kDa (monomer). In SDS-PAGE migrates as 80-85 kDa, reducing conditions. |
Purity : | >95%, by SDS-PAGE under reducing conditions and visualized by silver stain. |
Storage : | Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC). |
Gene Name : | Ager advanced glycosylation end product-specific receptor [ Mus musculus ] |
Official Symbol : | Ager |
Synonyms : | AGER; advanced glycosylation end product-specific receptor; advanced glycation end-products receptor; receptor for advanced glycosylation end products; advanced glycosylation end product-specific receptor variant 1; advanced glycosylation end product-specific receptor variant 2; advanced glycosylation end product-specific receptor variant 3; advanced glycosylation end product-specific receptor variant 4; advanced glycosylation end product-specific receptor variant 5; advanced glycosylation end product-specific receptor variant 6; RAGE; |
Gene ID : | 11596 |
mRNA Refseq : | NM_007425 |
Protein Refseq : | NP_031451 |
MIM : |
Products Types
◆ Lysates | ||
AGER-1480HCL | Recombinant Human AGER cell lysate | +Inquiry |
AGER-2546HCL | Recombinant Human RAGE 293 Cell Lysate | +Inquiry |
AGER-2215MCL | Recombinant Mouse AGER cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (20)
Ask a questionAGER is involved in bone metabolism and might influence osteoporosis and bone diseases.
AGER levels might serve as biomarkers for certain diseases, including diabetes.
AGER binds AGEs, initiating signaling cascades linked to inflammation, oxidative stress, and tissue damage.
AGER contributes to skin aging through oxidative stress and collagen damage.
AGER stands for "Advanced Glycosylation End-Product Specific Receptor," a cell surface receptor.
Yes, AGER activation contributes to inflammation and immune responses.
AGER activation can impair wound healing through inflammation and oxidative stress.
AGER contributes to neuroinflammation and might play a role in neurodegeneration.
AGER contributes to diabetic nephropathy and kidney dysfunction.
AGER binds to AGEs, initiating cellular signaling pathways linked to inflammation and oxidative stress.
AGER is implicated in lung diseases and inflammation, such as chronic obstructive pulmonary disease.
Researchers explore compounds that modulate AGER to mitigate its effects.
AGER contributes to diabetic complications by promoting inflammation and tissue damage.
AGER is studied for its implications in aging, diabetes, and various age-related diseases.
AGER plays a role in mediating cellular responses to advanced glycation end products (AGEs).
Consuming a low-AGE diet may help reduce AGER activation and its negative effects.
AGER activation affects immune cell functions and influences immune responses.
AGER activation is linked to cardiovascular diseases, including atherosclerosis.
Yes, besides AGEs, AGER interacts with other ligands like HMGB1 and β-amyloid.
Yes, ongoing research aims to uncover new roles and therapeutic targets related to AGER.
Customer Reviews (5)
Write a reviewIt's quality was evident in consistent results across replicates.
Protein consistently upregulated the expression of tissue-specific markers.
Gel electrophoresis bands displayed distinct separation, showcasing the product’s purity.
It’s consistent outcomes supported reliable statistical analysis.
Consistency and Compatibility Consistency in the product’s performance bolstered the credibility of our research findings.
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