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Active Recombinant Mouse Tfpi protein(Met1-Lys289), His-tagged

Cat.No. : Tfpi-981M
Product Overview : Recombinant Mouse Tfpi protein(NP_035706.1)(Met1-Lys289), fused with C-terminal His tag, was expressed in HEK293.
  • Specification
  • Gene Information
  • Related Products
similar : Tfpi
Alias : TFPI; tissue factor pathway inhibitor; extrinsic pathway inhibitor; lipoprotein-associated coagulation inhibitor; EPI; LACI; AW552122; A630013F22Rik;
Source : HEK293
Species : Mouse
Conjugate : C-His
Tag : C-His
Protein length : Met1-Lys289
Form : Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
MolecularMass : The secreted recombinant mouse TFPI consists of 272 amino acids and has a calculated molecular mass of 31 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 45 kDa protein in SDS-PAGE under reducing conditions.
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method
Purity : > 97 % as determined by SDS-PAGE
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
GeneName : Tfpi tissue factor pathway inhibitor [ Mus musculus ]
GeneNameWeblink : 21788
OfficialSymbol : Tfpi
OfficialSymbolWeblink : 21788
GeneID : 21788
GeneIDWeblink : 21788
mRNARefseq : NM_001177319
mRNARefseqWeblink : NM_001177319.1
ProteinRefseqWeblink : NP_001170790.1
Synonyms : TFPI; tissue factor pathway inhibitor; extrinsic pathway inhibitor; lipoprotein-associated coagulation inhibitor; EPI; LACI; AW552122; A630013F22Rik;
Synonyms : TFPI; tissue factor pathway inhibitor; extrinsic pathway inhibitor; lipoprotein-associated coagulation inhibitor; EPI; LACI; AW552122; A630013F22Rik;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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In which medical scenarios is monitoring TFPI protein particularly crucial? 06/20/2022

Monitoring TFPI levels is crucial in patients with a history of thrombotic events, individuals at high risk of clotting disorders, and those undergoing anticoagulant therapy.

Can TFPI protein be explored in the context of preventing complications in surgery or other medical procedures? 01/23/2022

Research suggests that manipulating TFPI levels might be explored to reduce thrombotic complications in surgical and medical settings, potentially improving patient outcomes.

Are there any challenges or risks associated with manipulating TFPI levels for therapeutic purposes? 07/27/2019

Manipulating TFPI levels may pose challenges, as it could potentially lead to bleeding disorders. Balancing the anticoagulant effects with the risk of bleeding is a critical consideration.

How does TFPI contribute to the regulation of inflammation in addition to its anticoagulant properties? 03/11/2017

TFPI has anti-inflammatory effects by inhibiting the activation of immune cells and downregulating inflammatory mediators. This dual role makes it a potential therapeutic target in conditions involving both coagulation and inflammation.

In what ways can TFPI protein be a target for drug development in the pharmaceutical industry? 04/22/2016

Pharmaceutical research can explore the development of drugs that either enhance or mimic the activity of TFPI, providing new avenues for anticoagulant therapies.

Customer Reviews (3)

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Reviews
03/04/2022

    This property is particularly beneficial for long-term trials or experiments with extended durations, ensuring consistent performance throughout the entire study period.

    05/31/2020

      Its purity and consistency have been extensively validated, minimizing any potential variability that could affect trial outcomes.

      07/22/2016

        Their extensive technical expertise and assistance are invaluable in overcoming any challenges that may arise during the experimental process.

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