Active Recombinant Mouse C2 Protein, His-tagged
Cat.No. : | C2-1012M |
Product Overview : | Recombinant Mouse C2 (Accession # O70350) Met1-Leu760, fused with a C-terminal 6-His tag, was produced in Mouse myeloma cell line, NS0-derived. |
- Specification
- Gene Information
- Related Products
Source : | Mammalian cells |
Species : | Mouse |
Tag : | His |
Predicted N Terminal : | Leu20 & Lys251 |
Form : | Supplied as a 0.2 µm filtered solution in Sodium Acetate and NaCl. |
Bio-activity : | Measured by its ability to cleave a colorimetric peptide substrate, N-carbobenzyloxy-Gly-Arg-ThioBenzyl ester (Z-GR-SBzl), in the presence of 5,5"Dithio-bis (2-nitrobenzoic acid) (DTNB). Edwards, K.M. et al. (1999) J. Biol. Chem. 274:30468.The specific activity is >200 pmol/min/µg, as measured under the described conditions. |
Molecular Mass : | Recombinant Mouse C2, His-tagged has a calculated MW of 58 kDa and 84 kDa. In SDS-PAGE migrates as 66-75 kDa & 90-110 kDa, reducing conditions. |
Protein length : | Met1-Leu760 |
Purity : | >95%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain at 5 µg per lane. |
Storage : | Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC). |
Reconstitution : | Reconstitute at 50 µg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin. |
Gene Name : | C2 complement component 2 (within H-2S) [ Mus musculus ] |
Official Symbol : | C2 |
Synonyms : | C2; complement component 2 (within H-2S); complement C2; C3/C5 convertase; complement factor C2; MHC complement component C2; classical-complement pathway C3/C5 convertase; |
Gene ID : | 12263 |
mRNA Refseq : | NM_013484 |
Protein Refseq : | NP_038512 |
MIM : |
Products Types
◆ Recombinant Protein | ||
C2-6878H | Active Recombinant Human C2 protein(Met1-Leu752), His-tagged | +Inquiry |
C2-1143M | Recombinant Mouse C2 Protein, His (Fc)-Avi-tagged | +Inquiry |
C2-1878C | Active Recombinant Cynomolgus C2 protein, His-tagged | +Inquiry |
C2-7847R | Recombinant Rat C2 protein, His & T7-tagged | +Inquiry |
C2-1032H | Active Recombinant Human C2 protein, His-tagged | +Inquiry |
◆ Native Protein | ||
C2-98H | Active Native Human C2 Protein | +Inquiry |
◆ Lysates | ||
C2-3068HCL | Recombinant Human C2 cell lysate | +Inquiry |
C2-001MCL | Recombinant Mouse C2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionYes, drugs targeting C2 or the complement system are being explored as potential treatments for autoimmune diseases to regulate the immune response.
Yes, the absence or dysfunction of C2 protein can be indicative of immune system disorders, and its levels can be assessed for diagnostic purposes.
Understanding C2's role in immune activation may contribute to vaccine design, potentially enhancing the effectiveness of vaccines by targeting the complement system.
Abnormal activation of the complement system, including C2, is associated with some autoimmune diseases where the immune system mistakenly attacks the body's own cells.
Yes, genetic variations can affect C2 protein expression and function, leading to variations in immune response among individuals.
Customer Reviews (3)
Write a reviewThe C2 protein comes highly recommended for its excellent performance in various research applications.
It has demonstrated exceptional effectiveness in WB experiments, showcasing its reliability and precision in detecting and quantifying specific targets.
Researchers can confidently rely on its capabilities to generate precise and significant results, enhancing the understanding of protein function and dynamics.
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