Active Recombinant Human ADAMTS4 Protein, His-tagged

• Cat.No.: ADAMTS4-1028H
• Product Overview: Recombinant Human ADAMTS4 (Accession # O75173) Phe213-Cys685, fused with a C-terminal 10-His tag, was produced in Chinese Hamster Ovary cell line, CHO-derived.

Specification

• Source: CHO Cells
• Species: Human
• Tag: His
• Predicted N Terminal: Phe213
• Form: Supplied as a 0.2 µm filtered solution in Sodium Acetate, CaCl2 and NaCl.
• Bio-activity: Measured by its ability to cleave Recombinant Human Aggrecan G1-IGD-G2 Domains.
• Molecular Mass: Recombinant Human ADAMTS4, His-tagged has a calculated MW of 53 kDa. In SDS-PAGE migrates as 58 kDa, reducing conditions.
• Protein length: Phe213-Cys685
• Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 [ Homo sapiens ]
• Official Symbol: ADAMTS4
• Synonyms: ADAMTS4; ADAM metallopeptidase with thrombospondin type 1 motif, 4; a disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 4; A disintegrin and metalloproteinase with thrombospondin motifs 4; ADAMTS 2; ADMP 1; KIAA0688; ADAM-TS4; ADAM-TS 4; aggrecanase-1; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 4; ADMP-1; ADAMTS-2; ADAMTS-4
• Gene ID: 9507
• mRNA Refseq: NM_005099
• Protein Refseq: NP_005090
• MIM: 603876
• UniProt ID: O75173
• Chromosome Location: 1q31-q32