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Active Recombinant Feline IL5 Protein, His-tagged

Cat.No. : IL5-1048F
Product Overview : Recombinant Feline IL5 (Accession # O77515) Ile20-Ser134, fused with a C-terminal 10-His tag, was produced in Mouse myeloma cell line, NS0-derived.
  • Specification
  • Gene Information
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Source : Mammalian cells
Species : Feline
Tag : His
Predicted N Terminal : Ile20
Form : Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
Bio-activity : Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. Kitamura, T. et al. (1989) J. Cell Physiol. 140:323.The ED50 for this effect is typically 2 - 8 ng/mL.
Molecular Mass : Recombinant Feline IL5, His-tagged has a calculated MW of 14.6 kDa. In SDS-PAGE migrates as 20 kDa, reducing conditions.
Protein length : Ile20-Ser134
Purity : >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Gene Name : IL5 interleukin 5 [ Felis catus (domestic cat) ]
Official Symbol : IL5
Synonyms : interleukin-5; interleukin-5; IL-5; T-cell replacing factor; TRF; eosinophil differentiation factor; interleukin 5 (colony-stimulating factor, eosinophil)
Gene ID : 493803
mRNA Refseq : NM_001009845.2 
Protein Refseq : NP_001009845.2
MIM :
UniProt ID : O77515
Chromosome Location : chromosome: A1

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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Which effect of IL5 in the treatment of tuberous sclerosis? 08/07/2022

Inhibit the creatinine kinase level in the blood of patients with tuberous sclerosis, reduce the inflammatory response, and improve the quality of life of patients.

Does there have any effect of IL5 in the treatment of allergic rhinitis? 07/07/2022

IL5 can reduce the number of eosinophils in the nasal mucosa of patients with allergic rhinitis, reducing the symptoms of allergic reactions, such as sneezing, runny nose and nasal congestion.

What is the main function of IL5? 03/04/2022

Stimulate the proliferation and differentiation of white blood cells, promote the function of the immune system, and is used to treat diseases such as asthma, allergic rhinitis, nodular sclerosis and some malignant tumors.

Does IL5 have side effects? 10/26/2019

Cause mild side effects such as headache, nausea, vomiting, and serious side effects such as allergic reactions if the dose is too large or allergic.

Can IL5 be administered orally? 07/24/2019

IL5 cannot be administered orally, only by injection or intravenous drip.

What is the effect of IL5 in the treatment of asthma? 02/14/2019

IL5 can reduce the number of eosinophils in the lungs of asthma patients, reduce the frequency and severity of asthma attacks, and improve the quality of life of patients.

Customer Reviews (3)

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Reviews
07/26/2022

    High efficacy and safety in clinical treatment.

    06/22/2022

      There are no structural or functional defects.

      01/31/2019

        The stability and activity are maintained well during long-term storage.

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