Active Recombinant Human BMPR1B, Fc-tagged, Biotinylated
Cat.No. : | BMPR1B-555H |
Product Overview : | The recombinant human BMPR1B-Fc fusion protein is expressed as a 342 amino acid protein consisting of Lys14 - Arg126 region of BMPR1B (UniProt accession #O00238) and a C-terminal Fc fusion from human IgG1, which exists as a dimer under non-reducing condition |
- Specification
- Gene Information
- Related Products
Source : | Human cells |
Species : | Human |
Tag : | Fc |
Form : | Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier & preservative free). The purified recombinant protein was labeled with Biotin (3-5 Biotin per molecule). |
Bio-activity : | Recombinant BMPR1B protein binds human BMP4 and blocks BMP4-induced signaling activity (e.g., alkaline phosphatase production in chondrogenic cells) |
Molecular Mass : | Calculated molecular mass (kDa): 38.4; Estimated by SDS-PAGE under reducing condition (kDa): ~45 |
AA Sequence : | KKEDGESTAPTPRPKVLRCKCHHHC PEDSVNNICSTDGYCFTMIEEDDSG LPVVTSGCLGLEGSDFQCRDTPIP HQRRSIECCTERNECNKDLHPTLPP LKNRDFVDGPIHHRASTGTHTCPPC PAPELLGGPSVFLFPPKPKDTLMI SRTPEVTCVVVDVSHEDPEVKFNWY VDGVEVHNAKTKPREEQYNSTYRVV SVLTVLHQDWLNGKEYKCKVSNK ALPAPIEKTISKAKGQPREPQVYTL PPSREEMTKNQVSLTCLVKGFYPSD IAVEWESNGQPENNYKTTPPVLDS DGSFFLYSKLTVDKSRWQQGNVFSC SVMHEALHNHYTQKSLSLSPGK |
Endotoxin : | <0.1 eu per 1 μg of purified recombinant protein determined by the |
Purity : | >95% judged by SDS-PAGE under reducing condition |
Storage : | The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles. |
Gene Name : | BMPR1B bone morphogenetic protein receptor, type IB [ Homo sapiens ] |
Official Symbol : | BMPR1B |
Synonyms : | BMPR1B; bone morphogenetic protein receptor, type IB; bone morphogenetic protein receptor type-1B; ALK6; CDw293; BMPR-1B; BMP type-1B receptor; activin receptor-like kinase 6; serine/threonine receptor kinase; ALK-6; |
Gene ID : | 658 |
mRNA Refseq : | NM_001203 |
Protein Refseq : | NP_001194 |
MIM : | 603248 |
UniProt ID : | O00238 |
Chromosome Location : | 4q23-q24 |
Pathway : | Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Ovarian Infertility Genes, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by BMP, organism-specific biosystem; TGF-beta signaling pathway, organism-specific biosystem; TGF-beta signaling pathway, conserved biosystem; |
Function : | ATP binding; SMAD binding; activin receptor activity, type II; metal ion binding; nucleotide binding; protein binding; protein serine/threonine kinase activity; receptor activity; receptor signaling protein serine/threonine kinase activity; transforming growth factor beta-activated receptor activity; transmembrane receptor protein serine/threonine kinase activity; transmembrane receptor protein serine/threonine kinase activity; transmembrane receptor protein serine/threonine kinase activity; |
Products Types
◆ Recombinant Protein | ||
BMPR1B-4369H | Recombinant Human BMPR1B Protein, His (Fc)-Avi-tagged | +Inquiry |
BMPR1B-376R | Recombinant Rhesus Macaque BMPR1B Protein, His (Fc)-Avi-tagged | +Inquiry |
BMPR1B-282H | Active Recombinant Human BMPR1B Protein | +Inquiry |
BMPR1B-26757TH | Recombinant Human BMPR1B | +Inquiry |
BMPR1B-301364H | Recombinant Human BMPR1B protein, GST-tagged | +Inquiry |
◆ Lysates | ||
BMPR1B-1166HCL | Recombinant Human BMPR1B cell lysate | +Inquiry |
BMPR1B-464HCL | Recombinant Human BMPR1B cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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