Active Recombinant Human TMIGD2, Fc-tagged, Biotinylated

• Cat.No.: TMIGD2-567H
• Product Overview: The recombinant human CD28H-Fc fusion is expressed as a 366-amino acid protein consisting of Leu23 - Gly150 region of CD28H (UniProt accession #Q96BF3) and a C-terminal Fc fusion from human IgG1, which exists as a dimer under non-reducing condition.

Specification

• Source: Human cells
• Species: Human
• Tag: Fc
• Form: Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier and preservative free). The purified recombinant protein was labeled with Biotin (3-5 Biotin per molecule).
• Bio-activity: Binds to its B7 family ligand, B7-H7/HHLA2 and iInhibit B7-H7-mediated signaling activity including IL-2 secretion in human T cells stimulated with anti-CD3 antibody.
• Molecular Mass: Calculated molecular mass 40.7 kDa; estimated by SDS-PAGE under reducing condition 55-60 kDa probably due to glycosylation
• Endotoxin: <0.1 eu per 1 μg of purified recombinant protein determined by the
• Purity: >95% judged by SDS-PAGE under reducing condition
• Storage: The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles.

Gene Information

• Gene Name: TMIGD2 transmembrane and immunoglobulin domain containing 2 [ Homo sapiens ]
• Official Symbol: TMIGD2
• Synonyms: IGPR1; IGPR-1
• Gene ID: 126259
• mRNA Refseq: NM_144615.2
• Protein Refseq: NP_653216.2
• MIM: 614715
• UniProt ID: Q96BF3
• Chromosome Location: 19p13.3