Active Recombinant Human CD44, Fc-tagged, Biotinylated
Cat.No. : | CD44-578H |
Product Overview : | The recombinant human CD44-Fc is expressed as a 470 amino acid protein consisting of Gln21 - Thr263 region of CDw44 (UniProt accession #P16070 - isoform 12 or CDw44) and a C-terminal Fc fusion from human IgG1, which exists as a dimer under non-reducing condition. |
- Specification
- Gene Information
- Related Products
Source : | Human cells |
Species : | Human |
Tag : | Fc |
Form : | Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier & preservative free). The purified recombinant protein was labeled with Biotin (3-5 Biotin per molecule). |
Bio-activity : | Immobilized CD44-Fc protein binds hyaluronan and anti-CD44 monoclonal antibodies, human IgG1, mouse IgG2a and rabbit IgG with high affinity (KD< 1 nm) in a functional> |
Molecular Mass : | Calculated molecular mass (kDa): 52; Estimated by SDS-PAGE under reducing condition (kDa): 80-90 |
AA Sequence : | QIDLNITCRFAGVFHVEKNGRYSIS RTEAADLCKAFNSTLPTMAQMEKAL SIGFETCRYGFIEGHVVIPRIHPN SICAANNTGVYILTSNTSQYDTYCF NASAPPEEDCTSVTDLPNAFDGPIT ITIVNRDGTRYVQKGEYRTNPEDI YPSNPTDDDVSSGSSSERSSTSGGY IFYTFSTVHPIPDEDSPWITDSTDR IPATRDQDTFHPSGGSHTTHGSES DGHSHGSQEGGANTTSGPIRTDKTH TCPPCPAPELLGGPSVFLFPPKPKD TLMISRTPEVTCVVVDVSHEDPEV KFNWYVDGVEVHNAKTKPREEQYNS TYRVVSVLTVLHQDWLNGKEYKCKV SNKALPAPIEKTISKAKGQPREP QVYTLPPSREEMTKNQVSLTCLVKG FYPSDIAVEWESNGQPENNYKTTPP VLDSDGSFFLYSKLTVDKSRWQQG NVFSCSVMHEALHNHYTQKSLSLSP GK |
Endotoxin : | <0.1 eu per 1 μg of purified recombinant protein determined by the |
Purity : | >95% judged by SDS-PAGE under reducing condition |
Storage : | The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles. |
Gene Name : | CD44 CD44 molecule (Indian blood group) [ Homo sapiens ] |
Official Symbol : | CD44 |
Synonyms : | CD44; CD44 molecule (Indian blood group); CD44 antigen (homing function and Indian blood group system) , MDU2, MDU3, MIC4; CD44 antigen; CD44R; chondroitin sulfate proteoglycan 8; CSPG8; HCELL; hematopoietic cell E and L selectin ligand; IN; MC56; Pgp1; epican; Hermes antigen; hyaluronate receptor; phagocytic glycoprotein 1; heparan sulfate proteoglycan; cell surface glycoprotein CD44; extracellular matrix receptor III; GP90 lymphocyte homing/adhesion receptor; hematopoietic cell E- and L-selectin ligand; homing function and Indian blood group system; LHR; MDU2; MDU3; MIC4; CDW44; HUTCH-I; ECMR-III; MGC10468; |
Gene ID : | 960 |
mRNA Refseq : | NM_000610 |
Protein Refseq : | NP_000601 |
MIM : | 107269 |
UniProt ID : | P16070 |
Chromosome Location : | 11p13 |
Pathway : | Cytokine Signaling in Immune system, organism-specific biosystem; ECM-receptor interaction, organism-specific biosystem; ECM-receptor interaction, conserved biosystem; Hematopoietic cell lineage, organism-specific biosystem; Hematopoietic cell lineage, conserved biosystem; Immune System, organism-specific biosystem; Interferon Signaling, organism-specific biosystem; |
Function : | binding; collagen binding; hyaluronic acid binding; hyaluronic acid binding; hyaluronic acid binding; hyalurononglucosaminidase activity; protein binding; receptor activity; contributes_to transmembrane signaling receptor activity; |
Products Types
◆ Recombinant Protein | ||
CD44-2152H | Recombinant Human CD44 Protein, His-tagged | +Inquiry |
CD44-3096H | Recombinant Human CD44 Protein, MYC/DDK-tagged | +Inquiry |
CD44-161H | Recombinant Human CD44 Protein, Fc-tagged | +Inquiry |
CD44-001H | Active Recombinant Human CD44 Protein, Myc/DDK-tagged | +Inquiry |
CD44-541H | Recombinant Human CD44 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
CD44-1090HCL | Recombinant Human CD44 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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