Active Recombinant Human TNFRSF10B, Fc-tagged, Biotinylated
Cat.No. : | TNFRSF10B-598H |
Product Overview : | The recombinant human DR5-Fc fusion is expressed as a 381 amino acid protein consisting of Ile56 - Pro208 region of DR5 (UniProt accession #O14763) and a C-terminal Fc from human IgG1, which exists as a dimer under non-reducing conditions. |
- Specification
- Gene Information
- Related Products
Source : | Human cells |
Species : | Human |
Tag : | Fc |
Form : | Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier & preservative free). The purified recombinant protein was labeled with Biotin (3-5 Biotin per molecule). |
Bio-activity : | Binds to its ligand human TRAIL and inhibits TRAIL-mediated signaling activity including TRAIL--induced cytotoxicity in L-929 mouse fibroblast cells. |
Molecular Mass : | Calculated molecular mass (kDa): 42.3; Estimated by SDS-PAGE under reducing condition (kDa): 50-55 |
Endotoxin : | <0.1 eu per 1 μg of purified recombinant protein determined by the |
Purity : | >95% judged by SDS-PAGE under reducing condition |
Storage : | The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles. |
Gene Name : | TNFRSF10B tumor necrosis factor receptor superfamily, member 10b [ Homo sapiens ] |
Official Symbol : | TNFRSF10B |
Synonyms : | TNFRSF10B; tumor necrosis factor receptor superfamily, member 10b; tumor necrosis factor receptor superfamily member 10B; CD262; DR5; KILLER; TRAIL R2; TRICK2A; TRICKB; Fas-like protein; death receptor 5; cytotoxic TRAIL receptor-2; apoptosis inducing receptor TRAIL-R2; apoptosis inducing protein TRICK2A/2B; TNF-related apoptosis-inducing ligand receptor 2; death domain containing receptor for TRAIL/Apo-2L; tumor necrosis factor receptor-like protein ZTNFR9; p53-regulated DNA damage-inducible cell death receptor(killer); TRICK2; ZTNFR9; TRAILR2; TRICK2B; TRAIL-R2; KILLER/DR5; |
Gene ID : | 8795 |
mRNA Refseq : | NM_003842 |
Protein Refseq : | NP_003833 |
MIM : | 603612 |
UniProt ID : | O14763 |
Chromosome Location : | 8p22-p21 |
Pathway : | Activation of Pro-Caspase 8, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Apoptosis, organism-specific biosystem; Caspase-8 is formed from procaspase-8, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; |
Function : | TRAIL binding; protein binding; receptor activity; |
Products Types
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Tnfrsf10b-6544M | Recombinant Mouse Tnfrsf10b Protein, Myc/DDK-tagged | +Inquiry |
TNFRSF10B-1999H | Recombinant Human TNFRSF10B Protein, MYC/DDK-tagged | +Inquiry |
TNFRSF10B-156H | Recombinant Human TNFRSF10B Protein, C-His-tagged | +Inquiry |
◆ Lysates | ||
TNFRSF10B-2829HCL | Recombinant Human TNFRSF10B cell lysate | +Inquiry |
TNFRSF10B-2397MCL | Recombinant Mouse TNFRSF10B cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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