Active Recombinant Human FGFR3, His-tagged, Biotinylated
Cat.No. : | FGFR3-609H |
Product Overview : | The recombinant human FGFR3 ECD protein is expressed as a 364 amino acid protein consisting of Glu23 - Gly375 region of FGFR3 (Uniprot accession #P22607 - isoform 1) and a C-terminal poly-His tag, which exists as a monomer under reducing and non-reducing conditions. It contains 8 potential N-linked glycosylation sites. |
- Specification
- Gene Information
- Related Products
Source : | Human cells |
Species : | Human |
Tag : | His |
Form : | Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier free). The purified recombinant protein was labeled with Biotin (3-5 Biotin per molecule). |
Bio-activity : | Binds and inhibits aFGF / FGF-acidic dependent proliferation of mouse fibroblast cells. |
Molecular Mass : | Calculated molecular mass (kDa): 39.5; Estimated by SDS-PAGE under reducing condition (kDa): 50-60 |
AA Sequence : | ESLGTEQRVVGRAAEVPGPEPGQQE QLVFGSGDAVELSCPPPGGGPMGPT VWVKDGTGLVPSERVLVGPQRLQV LNASHEDSGAYSCRQRLTQRVLCHF SVRVTDAPSSGDDEDGEDEAEDTGV DTGAPYWTRPERMDKKLLAVPAAN TVRFRCPAAGNPTPSISWLKNGREF RGEHRIGGIKLRHQQWSLVMESVVP SDRGNYTCVVENKFGSIRQTYTLD VLERSPHRPILQAGLPANQTAVLGS DVEFHCKVYSDAQPHIQWLKHVEVN GSKVGPDGTPYVTVLKTAGANTTD KELEVLSLHNVTFEDAGEYTCLAGN SIGFSHHSAWLVVLPAEEELVEADE AGSVYAGSTGHHHHHHHH |
Endotoxin : | <0.1 eu per 1 μg of purified recombinant protein determined by the |
Purity : | >95% judged by SDS-PAGE under reducing condition |
Storage : | The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles. |
Gene Name : | FGFR3 fibroblast growth factor receptor 3 [ Homo sapiens ] |
Official Symbol : | FGFR3 |
Synonyms : | FGFR3; fibroblast growth factor receptor 3; ACH, achondroplasia, thanatophoric dwarfism; CD333; CEK2; JTK4; FGFR-3; tyrosine kinase JTK4; hydroxyaryl-protein kinase; ACH; HSFGFR3EX; |
Gene ID : | 2261 |
mRNA Refseq : | NM_000142 |
Protein Refseq : | NP_000133 |
MIM : | 134934 |
UniProt ID : | P22607 |
Chromosome Location : | 4p16.3 |
Pathway : | Bladder cancer, organism-specific biosystem; Bladder cancer, conserved biosystem; Downstream signaling of activated FGFR, organism-specific biosystem; Endochondral Ossification, organism-specific biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; FGFR ligand binding and activation, organism-specific biosystem; |
Function : | ATP binding; fibroblast growth factor binding; fibroblast growth factor binding; fibroblast growth factor-activated receptor activity; nucleotide binding; protein binding; protein tyrosine kinase activity; protein tyrosine kinase activity; receptor activity; |
Products Types
◆ Recombinant Protein | ||
FGFR3-001H | Recombinant Human FGFR3 Protein, Fc-His-tagged | +Inquiry |
FGFR3-4135H | Recombinant Human FGFR3 Protein, Fc/His-tagged | +Inquiry |
FGFR3-207H | Recombinant Human FGFR3 Protein, hIgG-His-tagged | +Inquiry |
FGFR3-93H | Recombinant Human FGFR3 Protein (ECD), Fc-His-tagged(C-ter) | +Inquiry |
FGFR3-4136H | Active Recombinant Human FGFR3 Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
FGFR3-2596MCL | Recombinant Mouse FGFR3 cell lysate | +Inquiry |
FGFR3-001CCL | Recombinant Cynomolgus FGFR3 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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