Active Recombinant Human TNFRSF18 protein, His-tagged
Cat.No. : | TNFRSF18-2090H |
Product Overview : | Recombinant Human TNFRSF18 protein(NP_683700.1)(Met1-Glu161), fused with His tag, was expressed in HEK293. |
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Source : | HEK293 |
Species : | Human |
Tag : | His |
Form : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Bio-activity : | Measured by its binding ability in a functional ELISA. Immobilized TNFRSF18-His at 10 μg/mL (100 μL/well) can bind TNFSF18-mFc, the EC50 of TNFSF18-mFc is 20-60 ng/mL. |
Molecular Mass : | The recombinant human TNFRSF18 consists 147 amino acids and predicts a molecular mass of 16 kDa. As a result of glycosylation, it migrates as an approximately 25.44 KDa band in SDS-PAGE under reducing conditions. |
Protein Length : | Met1-Glu161 |
Endotoxin : | < 1.0 EU per μg protein as determined by the LAL method. |
Purity : | > 95 % as determined by SDS-PAGE. |
Storage : | Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | TNFRSF18 tumor necrosis factor receptor superfamily, member 18 [ Homo sapiens ] |
Official Symbol : | TNFRSF18 |
Synonyms : | TNFRSF18; tumor necrosis factor receptor superfamily, member 18; tumor necrosis factor receptor superfamily member 18; AITR; CD357; GITR; activation-inducible TNFR family receptor; glucocorticoid-induced TNFR-related protein; TNF receptor superfamily activation-inducible protein; GITR-D; |
Gene ID : | 8784 |
mRNA Refseq : | NM_004195 |
Protein Refseq : | NP_004186 |
MIM : | 603905 |
UniProt ID : | Q9Y5U5 |
Products Types
◆ Recombinant Protein | ||
TNFRSF18-663M | Recombinant Mouse TNFRSF18 Protein, Fc-tagged | +Inquiry |
TNFRSF18-662M | Recombinant Mouse TNFRSF18 Protein | +Inquiry |
TNFRSF18-665R | Recombinant Rat TNFRSF18 Protein, Fc-tagged | +Inquiry |
TNFRSF18-154H | Recombinant Human TNFRSF18 Protein, C-His-tagged | +Inquiry |
TNFRSF18-894M | Recombinant Mouse TNFRSF18 Protein (Met1-His153), MlgG1 Fc-tagged | +Inquiry |
◆ Lysates | ||
TNFRSF18-1245RCL | Recombinant Rat TNFRSF18 cell lysate | +Inquiry |
TNFRSF18-1143HCL | Recombinant Human TNFRSF18 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionClinical trials are investigating TNFRSF18 agonists, such as monoclonal antibodies, in combination with other cancer treatments in various cancer types.
As of my knowledge cutoff date in January 2022, there were no approved TNFRSF18-targeted therapies for cancer. However, this may have changed since then.
Side effects may include immune-related adverse events, similar to those seen with other immunotherapies, and can range from mild to severe.
TNFRSF18-targeted therapies may enhance the body's immune response against cancer cells, leading to better tumor control and improved patient outcomes.
Yes, combination therapies involving TNFRSF18 agonists and other immunotherapies are under investigation to improve treatment efficacy.
Customer Reviews (3)
Write a reviewThis flexibility enables researchers like myself to tailor TNFRSF18 protein experiments to our unique needs, enhancing the reliability and relevance of the obtained results.
Their commitment to delivering exceptional products and assisting with any challenges that may arise ensures a successful and rewarding experimental journey.
The TNFRSF18 protein offered by the manufacturer is of exceptional quality, and it meets the rigorous standards necessary for my experimental needs.
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