Active Recombinant Human CTSC, His-tagged

• Cat.No.: CTSC-2510H
• Product Overview: Recombinant Human CTSC (Asp25-Leu463) fussed with 10-His tag at C-terminal was expressed in NS0 cells.

Specification

• Source: Mammalian cells
• Species: Human
• Tag: His
• Predicted N Terminal: Asp25
• Form: Supplied as a 0.2 µm filtered solution in MES and NaCl.
• Bio-activity: Measured by its ability to cleave the fluorogenic peptide substrate, Gly-Arg-7-amido-4-methylcoumarin (GR-AMC).The specific activity is >200 pmol/min/µg, as measured under the described conditions.
• Molecular Mass: Predicted Molecular Mass: 51 kDa;SDS-PAGE: 60 kDa, reducing conditions
• Protein length: Asp25-Leu463
• Endotoxin: < 1.0 EU per 1 μg of the protein by the LAL method.
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.6 months from date of receipt, -20 to -70 centigrade as supplied.3 months, -20 to -70 centigrade under sterile conditions after opening.
• Shipping: The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.

Gene Information

• Gene Name: CTSC cathepsin C [ Homo sapiens ]
• Official Symbol: CTSC
• Synonyms: CTSC; cathepsin C; PALS, PLS; dipeptidyl peptidase 1; DPP1; cathepsin J; dipeptidyl peptidase I; dipeptidyl transferase; dipeptidyl-peptidase I; JP; HMS; JPD; PLS; CPPI; DPPI; PALS; DPP-I
• Gene ID: 1075
• mRNA Refseq: NM_001114173
• Protein Refseq: NP_001107645
• MIM: 602365
• UniProt ID: P53634
• Chromosome Location: 11q14.2
• Pathway: Lysosome, organism-specific biosystem; Lysosome, conserved biosystem
• Function: chloride ion binding; cysteine-type endopeptidase activity; cysteine-type peptidase activity; identical protein binding; peptidase activity; protein self-association