Active Recombinant Human PDCD1LG2, Fc-tagged, Biotinylated
Cat.No. : | PDCD1LG2-661H |
Product Overview : | The recombinant human PD-L2-Fc fusion is expressed as a 429 amino acid protein consisting of Leu20 - Thr220 region of PD-L2 (UniProt accession #Q9BQ51) and a C-terminal Fc from human IgG1, which exists as a dimer under non-reducing conditions. |
- Specification
- Gene Information
- Related Products
Source : | Human cells |
Species : | Human |
Tag : | Fc |
Form : | Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier & preservative free). The purified recombinant protein was labeled with Biotin (3-5 Biotin per molecule). |
Bio-activity : | Binds to its receptor PD-1 in a functional ELISA. Blocks its ligand PD-L1"s and PD-L2"s binding to its receptor and mediated signaling activity. |
Molecular Mass : | Calculated molecular mass 48.2 kDa; estimated by SDS-PAGE under reducing condition ~60 kDa (probably due to glycosylation) |
AA Sequence : | LFTVTVPKELYIIEHGSNVTLECNF DTGSHVNLGAITASLQKVENDTSPH RERATLLEEQLPLGKASFHIPQVQ VRDEGQYQCIIIYGVAWDYKYLTLK VKASYRKINTHILKVPETDEVELTC QATGYPLAEVSWPNVSVPANTSHS RTPEGLYQVTSVLRLKPPPGRNFSC VFWNTHVRELTLASIDLQSQMEPRT HPTSTGTHTCPPCPAPELLGGPSV FLFPPKPKDTLMISRTPEVTCVVVD VSHEDPEVKFNWYVDGVEVHNAKTK PREEQYNSTYRVVSVLTVLHQDWL NGKEYKCKVSNKALPAPIEKTISKA KGQPREPQVYTLPPSREEMTKNQVS LTCLVKGFYPSDIAVEWESNGQPE NNYKTTPPVLDSDGSFFLYSKLTVD KSRWQQGNVFSCSVMHEALHNHYTQ KSLSLSPGK |
Endotoxin : | <0.1 eu per 1 μg of purified recombinant protein determined by the lal>0.1> |
Purity : | >95% judged by SDS-PAGE under reducing condition |
Storage : | The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles. |
Gene Name : | PDCD1LG2 programmed cell death 1 ligand 2 [ Homo sapiens ] |
Official Symbol : | PDCD1LG2 |
Synonyms : | PDCD1LG2; programmed cell death 1 ligand 2; B7 dendritic cell molecule; B7 DC; bA574F11.2; Btdc; CD273; PD L2; PDL2; B7-DC; PD-1 ligand 2; PD-1-ligand 2; PDCD1 ligand 2; butyrophilin B7-DC; programmed death ligand 2; B7DC; PD-L2; PDCD1L2; MGC142238; MGC142240; |
Gene ID : | 80380 |
mRNA Refseq : | NM_025239 |
Protein Refseq : | NP_079515 |
MIM : | 605723 |
UniProt ID : | Q9BQ51 |
Chromosome Location : | 9p24.2 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Costimulation by the CD28 family, organism-specific biosystem; Immune System, organism-specific biosystem; PD-1 signaling, organism-specific biosystem; |
Function : | molecular_function; protein tyrosine phosphatase activity; receptor activity; |
Products Types
◆ Recombinant Protein | ||
PDCD1LG2-715H | Recombinant Human PDCD1LG2 Protein | +Inquiry |
PDCD1LG2-719M | Recombinant Mouse PDCD1LG2 Protein, Fc-tagged | +Inquiry |
PDCD1LG2-841M | Recombinant Mouse PDCD1LG2 Protein (Met1-Arg219), His-tagged, Biotinylated | +Inquiry |
PDCD1LG2-3158R | Recombinant Rhesus Macaque PDCD1LG2 Protein, His (Fc)-Avi-tagged | +Inquiry |
PDCD1LG2-2565H | Recombinant Human PDCD1LG2 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
PDCD1LG2-2721HCL | Recombinant Human PDCD1LG2 cell lysate | +Inquiry |
PDCD1LG2-1738MCL | Recombinant Mouse PDCD1LG2 cell lysate | +Inquiry |
PDCD1LG2-951CCL | Recombinant Cynomolgus PDCD1LG2 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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