Active Recombinant Human PDGFRA, Fc-tagged, Biotinylated
Cat.No. : | PDGFRA-662H |
Product Overview : | The recombinant human PDGFRA-Fc fusion is expressed as a 733 amino acid protein consisting of Gln24 - Ala528 region of PDGFRA and a C-terminal Fc from human IgG1, which exists as a dimer under non-reducing conditions. |
- Specification
- Gene Information
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Source : | Human cells |
Species : | Human |
Tag : | Fc |
Form : | Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier & preservative free). The purified recombinant protein was labeled with Biotin (3-5 Biotin per molecule). |
Bio-activity : | Binds human PDGF family members (PDGFA, PDGFB and PDGFC) and blocks PDGF-mediated signaling activity in fibroblast cells. |
Molecular Mass : | Calculated molecular mass (kDa): 82.1; Estimated by SDS-PAGE under reducing condition (kDa): 90-100 |
AA Sequence : | QLSLPSILPNENEKVVQLNSSFSLR CFGESEVSWQYPMSEEESSDVEIRN EENNSGLFVTVLEVSSASAAHTGL YTCYYNHTQTEENELEGRHIYIYVP DPDVAFVPLGMTDYLVIVEDDDSAI IPCRTTDPETPVTLHNSEGVVPAS YDSRQGFNGTFTVGPYICEATVKGK KFQTIPFNVYALKATSELDLEMEAL KTVYKSGETIVVTCAVFNNEVVDL QWTYPGEVKGKGITMLEEIKVPSIK LVYTLTVPEATVKDSGDYECAARQA TREVKEMKKVTISVHEKGFIEIK PTFSQLEAVNLHEVKHFVVEVRAYP PPRISWLKNNLTLIENLTEITTDVE KIQEIRYRSKLKLIRAKEEDSGHY TIVAQNEDAVKSYTFELLTQVPSSI LDLVDDHHGSTGGQTVRCTAEGTPL PDIEWMICKDIKKCNNETSWTILA NNVSNIITEIHPRDRSTVEGRVTFA KVEETIAVRCLAKNLLGAENRELKL VAPTLRSELTVASTGTHTCPPCPA PELLGGPSVFLFPPKPKDTLMISRT PEVTCVVVDVSHEDPEVKFNWYVDG VEVHNAKTKPREEQYNSTYRVVS VLTVLHQDWLNGKEYKCKVSNKALP APIEKTISKAKGQPREPQVYTLPPS REEMTKNQVSLTCLVKGFYPSDIA VEWESNGQPENNYKTTPPVLDSDGS FFLYSKLTVDKSRWQQGNVFSCSVM HEALHNHYTQKSLSLSPGK |
Endotoxin : | <0.1 eu per 1 μg of purified recombinant protein determined by the lal>0.1> |
Purity : | >95% judged by SDS-PAGE under reducing condition |
Storage : | The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles. |
Gene Name : | PDGFRA platelet-derived growth factor receptor, alpha polypeptide [ Homo sapiens ] |
Official Symbol : | PDGFRA |
Synonyms : | PDGFRA; platelet-derived growth factor receptor, alpha polypeptide; platelet-derived growth factor receptor alpha; CD140a; PDGFR2; PDGFR-alpha; PDGF-R-alpha; CD140a antigen; PDGFRA/BCR fusion; CD140 antigen-like family member A; platelet-derived growth factor receptor 2; alpha-type platelet-derived growth factor receptor; rearranged-in-hypereosinophilia-platelet derived growth factor receptor alpha fusion protein; CD140A; PDGFR-2; RHEPDGFRA; MGC74795; |
Gene ID : | 5156 |
mRNA Refseq : | NM_006206 |
Protein Refseq : | NP_006197 |
MIM : | 173490 |
UniProt ID : | P16234 |
Chromosome Location : | 4q12 |
Pathway : | ATF-2 transcription factor network, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Downstream signal transduction, organism-specific biosystem; Endocytosis, organism-specific biosystem; |
Function : | ATP binding; nucleotide binding; phosphatidylinositol 3-kinase binding; platelet-derived growth factor alpha-receptor activity; platelet-derived growth factor alpha-receptor activity; platelet-derived growth factor binding; platelet-derived growth factor binding; platelet-derived growth factor receptor binding; protein homodimerization activity; protein tyrosine kinase activity; receptor activity; transmembrane receptor protein tyrosine kinase activity; vascular endothelial growth factor binding; vascular endothelial growth factor-activated receptor activity; |
Products Types
◆ Recombinant Protein | ||
PDGFRA-188H | Recombinant Human PDGFRA Protein, His-tagged | +Inquiry |
PDGFRA-2050H | Recombinant Human PDGFRA Protein, Fc/His-tagged | +Inquiry |
Pdgfra-99M | Recombinant Mouse Pdgfra Protein, His (Fc)-Avi-tagged | +Inquiry |
PDGFRA-1633H | Recombinant Human PDGFRA Protein, His (Fc)-Avi-tagged | +Inquiry |
PDGFRA-3560H | Recombinant Human PDGFRA, His-tagged | +Inquiry |
◆ Lysates | ||
PDGFRA-824RCL | Recombinant Rat PDGFRA cell lysate | +Inquiry |
PDGFRA-001HCL | Recombinant Human PDGFRA cell lysate | +Inquiry |
PDGFRA-2657HCL | Recombinant Human PDGFRA cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1616 | U2OS PDGFRa Bioassay Kit | +Inquiry |
Kit-1615 | PDGFRa Functional Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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