Active Recombinant Human TNFRSF11A, Fc-tagged, Biotinylated
Cat.No. : | TNFRSF11A-663H |
Product Overview : | The recombinant human RANK-Fc fusion is expressed as a 411 amino acid protein consisting of Ile30 - Pro212 region of RANK (UniProt accession #Q9Y6Q6) and a C-terminal Fc from human IgG1, which exists as a dimer/tetramer/oligomer under non-reducing conditions. |
- Specification
- Gene Information
- Related Products
Source : | Human cells |
Species : | Human |
Tag : | Fc |
Form : | Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier & preservative free). The purified recombinant protein was labeled with Biotin (3-5 Biotin per molecule). |
Bio-activity : | Binds to its ligand human RANKL and inhibits RANKL-induced signaling activity including osteoclast differentiation in mouse monocyte/macrophage cells RAW 264.7. |
Molecular Mass : | Calculated molecular mass (kDa): 45.7; Estimated by SDS-PAGE under reducing condition (kDa): ~55 |
Endotoxin : | <0.1 eu per 1 μg of purified recombinant protein determined by the lal>0.1> |
Purity : | >95% judged by SDS-PAGE under reducing condition |
Storage : | The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles. |
Gene Name : | TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator [ Homo sapiens ] |
Official Symbol : | TNFRSF11A |
Synonyms : | TNFRSF11A; tumor necrosis factor receptor superfamily, member 11a, NFKB activator; tumor necrosis factor receptor superfamily, member 11a, activator of NFKB; tumor necrosis factor receptor superfamily member 11A; CD265; RANK; receptor activator of NF-KB; osteoclast differentiation factor receptor; receptor activator of nuclear factor-kappa B; loss of heterozygosity, 18, chromosomal region 1; FEO; OFE; ODFR; OSTS; PDB2; OPTB7; TRANCER; LOH18CR1; |
Gene ID : | 8792 |
mRNA Refseq : | NM_003839 |
Protein Refseq : | NP_003830 |
MIM : | 603499 |
UniProt ID : | Q9Y6Q6 |
Chromosome Location : | 18q22.1 |
Pathway : | Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Osteoclast Signaling, organism-specific biosystem; Osteoclast differentiation, organism-specific biosystem; Osteoclast differentiation, conserved biosystem; Rheumatoid arthritis, organism-specific biosystem; Rheumatoid arthritis, conserved biosystem; |
Function : | cytokine binding; metal ion binding; protein binding; receptor activity; transmembrane signaling receptor activity; tumor necrosis factor-activated receptor activity; |
Products Types
◆ Recombinant Protein | ||
Tnfrsf11a-186R | Recombinant Rat Tnfrsf11a Protein, His-tagged | +Inquiry |
Tnfrsf11a-112M | Recombinant Mouse Tnfrsf11a Protein, His (Fc)-Avi-tagged | +Inquiry |
TNFRSF11A-235H | Recombinant Human TNFRSF11A Protein, His (Fc)-Avi-tagged | +Inquiry |
TNFRSF11A-155H | Recombinant Human TNFRSF11A Protein, His-tagged | +Inquiry |
Tnfrsf11a-185M | Recombinant Mouse Tnfrsf11a Protein, His-tagged | +Inquiry |
◆ Lysates | ||
TNFRSF11A-1413RCL | Recombinant Rat TNFRSF11A cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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