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Recombinant Human PRKCD protein, His-tagged

Cat.No. : PRKCD-357H
Product Overview : Recombinant Human PRKCD(Met1-Asp676) fussed with His tag at C-terminal was expressed in HEK293.
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Description : Protein Kinase C Delta Type (PRKCD) is a member of the AGC Ser/Thr protein kinase family of protein kinase superfamily. PKC family members phosphorylate a variety of protein targets and are known to be involved in diverse cellular signaling pathways. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. PRKCD serves as a major receptor for phorbol esters, a class of tumor promoters. PRKCD is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types.
Source : HEK293
Species : Human
Tag : His
AA Sequence : MAPFLRIAFNSYELGSLQAEDEANQ PFCAVKMKEALSTERGKTLVQKKPT MYPEWKSTFD AHIY EGRVIQIVLMRAAEEPVSEVTVGVS VLAERCKKNNGKAEFWLDLQPQAKV LMSVQY FLEDVDCK QSMRSEDEAKFPTMNRRGAIKQAKI HYIKNHEFIATFFGQPTFCSVCKDF VW GLNKQGYKCRQC NAAIHKKCIDKIIGRCTGTAANSRD TIFQKERFNIDMPHRFKVHNYMS PTFCDHCGSLLWGLVK QGLKCEDCGMNVHHKCREKVANLCG INQKLLAEALNQVTQRASR RSDSASSEPVGIYQGFEKKT GVAGEDMQDNSGTYGKIWEGSSKCN INNFIFHKVLGKGSF GKVLLGELKGRGEYFAIKALKKDV VLIDDDVECTMVEKRVLTLAAENPF LTHLICTFQTK DHLFFVMEFLNGGDLMYHIQDKGRF ELY RATFYAAEIMCGLQFLHSKGIIYRD LKLDNVL LDRDGHIKIADFGMCKENIFGESRA STFCGTP DYIAPEILQGLKYTFSVDWWSFGVL LYE MLIGQSPFHGDDEDELFESIRVDTP HYPRWITKESK DILEKLFEREPTKRLGVTGNIKIH PFFKTINWTLLEKRRLEPPFRPKVK SPRDYSNFDQEFLNE KARLSYSDKNLIDSMDQSAF AGFSFVNPKFEHLLEDLDHHHHHH
Endotoxin : Less than 0.1 ng/μg (1 IEU/μg).
Purity : Greater than 95% as determined by reducing SDS-PAGE.
Storage : Store at < -20 centigrade, stable for 6 months after receipt.Please minimize freeze-thaw cycles.
Gene Name : PRKCD protein kinase C, delta [ Homo sapiens ]
Official Symbol : PRKCD
Synonyms : PRKCD; protein kinase C, delta; protein kinase C delta type; protein kinase C delta VIII; tyrosine-protein kinase PRKCD; MAY1; PKCD; nPKC-delta; MGC49908;
Gene ID : 5580
mRNA Refseq : NM_006254
Protein Refseq : NP_006245
MIM : 176977
UniProt ID : Q05655
Chromosome Location : 3p21.31
Pathway : Alpha-synuclein signaling, organism-specific biosystem; Alpha6-Beta4 Integrin Signaling Pathway, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptotic cleavage of cellular proteins, organism-specific biosystem; Apoptotic executionphase, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; Ca-dependent events, organism-specific biosystem;
Function : ATP binding; calcium-independent protein kinase C activity; enzyme activator activity; enzyme binding; insulin receptor substrate binding; metal ion binding; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; protein C-terminus binding; protein binding; protein kinase activity; protein serine/threonine kinase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Are there any side effects associated with targeting PRKCD in therapy? 10/19/2021

Like any targeted therapy, there may be side effects associated with PRKCD inhibitors, and ongoing clinical trials aim to assess the safety profile of these potential treatments.

Is PRKCD involved in the regulation of inflammation? 11/22/2019

Yes, PRKCD is implicated in the regulation of inflammation, and its modulation could be explored for the development of anti-inflammatory therapies.

Can PRKCD be a target for personalized medicine? 09/25/2019

The role of PRKCD in various diseases suggests that it could be a potential target for personalized medicine, tailoring treatments based on an individual's molecular profile.

How does PRKCD impact immune response? 11/22/2017

PRKCD has been found to influence immune response, and its modulation could potentially be harnessed to enhance the body's ability to fight off infections or respond to immunotherapies.

Can PRKCD be a potential biomarker for cancer diagnosis? 07/05/2016

Research suggests that the expression levels of PRKCD may serve as a biomarker for certain cancers, aiding in early diagnosis and prognosis.

Customer Reviews (3)

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Reviews
09/12/2021

    Their knowledgeable and responsive team has consistently demonstrated their ability to address any concerns or challenges I have encountered along the way.

    04/11/2020

      Its versatility allows for exploring its various roles and functions, shedding light on its significance in crucial biochemical pathways and cellular processes.

      06/17/2018

        Their support has been invaluable in troubleshooting and providing efficient solutions, enhancing the overall efficiency and productivity of my experiments.

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