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Recombinant Human NNMT protein, MYC/DDK-tagged

Cat.No. : NNMT-452H
Product Overview : Recombinant Human NNMT fused with MYC/DDK tag at C-terminal was expressed in HEK293.
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  • Gene Information
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Description : N-methylation is one method by which drug and other xenobiotic compounds are metabolized by the liver. This gene encodes the protein responsible for this enzymatic activity which uses S-adenosyl methionine as the methyl donor.
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 29.4 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : NNMT nicotinamide N-methyltransferase [ Homo sapiens ]
Official Symbol : NNMT
Synonyms : NNMT; nicotinamide N-methyltransferase;
Gene ID : 4837
mRNA Refseq : NM_006169
Protein Refseq : NP_006160
MIM : 600008
UniProt ID : P40261
Chromosome Location : 11q23.1
Pathway : Biological oxidations, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Methylation, organism-specific biosystem; Nicotinate and nicotinamide metabolism, organism-specific biosystem; Nicotinate and nicotinamide metabolism, conserved biosystem; Phase II conjugation, organism-specific biosystem;
Function : methyltransferase activity; nicotinamide N-methyltransferase activity; transferase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can NNMT protein be used as a biomarker for diseases? 04/18/2023

Yes, elevated levels of NNMT in blood or tissues have been proposed as potential biomarkers for certain diseases.

How does NNMT affect cardiovascular health? 07/01/2022

Elevated NNMT levels have been associated with increased risk of cardiovascular diseases, making it a potential therapeutic target.

Are there any drugs targeting NNMT protein? 08/15/2019

Research is ongoing to develop drugs that modulate NNMT activity as potential treatments for diseases where NNMT is implicated.

How is NNMT protein clinically relevant? 04/11/2017

NNMT has been linked to several diseases and health conditions, making it a potential target for therapeutic interventions.

What diseases are associated with NNMT dysfunction? 06/10/2016

NNMT dysregulation has been associated with metabolic disorders, cancer, neurodegenerative diseases, and cardiovascular diseases.

Customer Reviews (3)

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Reviews
01/22/2021

    Its high specificity and functional integrity ensure accurate and reproducible data, allowing researchers to draw meaningful conclusions from their experiments.

    11/10/2018

      This protein is known for its exceptional quality and purity, providing reliable and consistent results.

      01/25/2017

        The NNMT protein offers numerous advantages in trials and research experiments, making it an excellent choice for researchers.

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