Recombinant Human QPCT protein, His-tagged
Cat.No. : | QPCT-36H |
Product Overview : | Recombinant human QPCT, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
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Description : | QPCT, also known as glutaminyl-peptide cyclotransferase, is responsible for the biosynthesis of pyroglutamyl peptides. This protein has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. It catalyzes N-terminal pyroglutamate formation. In vitro, it catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides [Glu-3]-beta-amyloid. |
Source : | Insect cell |
Species : | Human |
Tag : | His |
Form : | Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. |
Molecular Mass : | 38.7kDa (339aa)28-40kDa (SDS-PAGE under reducing conditions) |
AA Sequence : | VSPSASAWPE EKNYHQPAIL NSSALRQIAE GTSISEMWQN DLQPLLIERY PGSPGSYAAR QHIMQRIQRL QADWVLEIDT FLSQTPYGYRSFSNIISTLN PTAKRHLVLA CHYDSKYFSH WNNRVFVGAT DSAVPCAMML ELARALDKKL LSLKTVSDSK PDLSLQLIFF DGEEAFLHWSPQDSLYGSRH LAAKMASTPH PPGARGTSQL HGMDLLVLLD LIGAPNPTFP NFFPNSARWF ERLQAIEHEL HELGLLKDHS LEGRYFQNYSYGGVIQDDHI PFLRRGVPVL HLIPSPFPEV WHTMDDNEEN LDESTIDNLN KILQVFVLEY LHLHHHHHH |
Endotoxin : | < 1.0 EU per 1 microgram of protein (determined by LAL method) |
Purity : | >90% by SDS – PAGE |
Storage : | Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.5mg/ml (determined by Absorbance at 280nm) |
Gene Name : | QPCT glutaminyl-peptide cyclotransferase [ Homo sapiens ] |
Official Symbol : | QPCT |
Synonyms : | QPCT; glutaminyl-peptide cyclotransferase; GCT; glutaminyl cyclase; QC; EC; glutamyl cyclase; glutaminyl-tRNA cyclotransferase; sQC; |
Gene ID : | 25797 |
mRNA Refseq : | NM_012413 |
Protein Refseq : | NP_036545 |
MIM : | 607065 |
UniProt ID : | Q16769 |
Chromosome Location : | 2p22 |
Function : | glutaminyl-peptide cyclotransferase activity; metal ion binding; peptidase activity; transferase activity, transferring acyl groups; zinc ion binding; |
Products Types
◆ Recombinant Protein | ||
QPCT-1822H | Recombinant Human QPCT Protein, His (Fc)-Avi-tagged | +Inquiry |
QPCT-156H | Recombinant Human QPCT Protein, MYC/DDK-tagged | +Inquiry |
QPCT-2139M | Recombinant Mouse QPCT Protein (36-362 aa), His-tagged | +Inquiry |
QPCT-1347H | Recombinant Human QPCT Protein, His-SUMO-tagged | +Inquiry |
QPCT-2269M | Recombinant Mouse QPCT Protein (36-362 aa), His-tagged | +Inquiry |
◆ Lysates | ||
QPCT-001HCL | Recombinant Human QPCT cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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