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Recombinant Human PGM1 protein, His-tagged

Cat.No. : PGM1-41H
Product Overview : Recombinant human PGM1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
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Description : PGM1 also known as Phosphoglucomutase-1 isoform 1. PGM1 belongs to the phosphohexose mutase family. There are several PGM isozymes, which are catalyze the transfer of phosphate between the 1 and 6 positions of glucose. In most cell types, PGM1 isozymes predominate, representing about 90% of total PGM activity. Defects in PGM1 are the cause of glycogen storage disease type 14.
Source : E. coli
Species : Human
Tag : His
Form : Liquid. In Phosphate Buffered Saline(pH 7.4) containing 10% glycerol
Molecular Mass : 63.8 kDa (585aa)
AA Sequence : MGSSHHHHHH SSGLVPRGSH MGSMVKIVTV KTQAYQDQKP GTSGLRKRVK VFQSSANYAE NFIQSIISTV EPAQRQEATL VVGGDGRFYM KEAIQLIARI AAANGIGRLV IGQNGILSTP AVSCIIRKIK AIGGIILTAS HNPGGPNGDF GIKFNISNGG PAPEAITDKI FQISKTIEEY AVCPDLKVDL GVLGKQQFDL ENKFKPFTVE IVDSVEAYAT MLRSIFDFSA LKELLSGPNR LKIRIDAMHG VVGPYVKKIL CEELGAPANS AVNCVPLEDF GGHHPDPNLT YAADLVETMK SGEHDFGAAF DGDGDRNMIL GKHGFFVNPS DSVAVIAANI FSIPYFQQTG VRGFARSMPT SGALDRVASA TKIALYETPT GWKFFGNLMD ASKLSLCGEE SFGTGSDHIR EKDGLWAVLA WLSILATRKQ SVEDILKDHW QKYGRNFFTR YDYEEVEAEG ANKMMKDLEA LMFDRSFVGK QFSANDKVYT VEKADNFEYS DPVDGSISRN QGLRLIFTDG SRIVFRLSGT GSAGATIRLY IDSYEKDVAK INQDPQVMLA PLISIALKVS QLQERTGRTA PTVIT
Purity : >95% by SDS - PAGE
Storage : Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
Concentration : 1mg/ml (determined by Absorbance at 280nm)
Gene Name : PGM1 phosphoglucomutase 1 [ Homo sapiens ]
Official Symbol : PGM1
Synonyms : PGM1; phosphoglucomutase 1; phosphoglucomutase-1; PGM 1; glucose phosphomutase 1; GSD14;
Gene ID : 5236
mRNA Refseq : NM_001172818
Protein Refseq : NP_001166289
MIM : 171900
UniProt ID : P36871
Chromosome Location : 1p22.1
Pathway : Amino sugar and nucleotide sugar metabolism, organism-specific biosystem; Amino sugar and nucleotide sugar metabolism, conserved biosystem; GDP-glucose biosynthesis, organism-specific biosystem; GDP-glucose biosynthesis, conserved biosystem; Galactose metabolism, organism-specific biosystem; Galactose metabolism, conserved biosystem; Glucose metabolism, organism-specific biosystem;
Function : isomerase activity; magnesium ion binding; phosphoglucomutase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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