Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Active Recombinant Human Histone Deacetylase 3, His GST-tagged

Cat.No. : HDAC3-394H
Product Overview : Full Length Human HDAC3– Class I, 53kD with his His & GST tag.
  • Specification
  • Gene Information
  • Related Products
Cat. No. : HDAC3-394H
Description : Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
Source : HDAC3 was cloned from human brain cDNA and expressed in insect cells using a baculoviral expression system.
Purity : Purified, active enzyme.
Purification Procedure : Ni2+ Affinity Column & Glutathione
Activity : 1000 units per vial. 1 unit is defined as the amount of enzyme that will convert 1picomole per minute per ug of protein at pH8 at 30°C.
Stability/Shelf-life : >6 months from date of shipment
Buffer Composition : 25mM Tris pH8, 120mM NaCl, 0.05% Tween-20 & 40% Glycerol.
Storage : –80°C
Gene Name : HDAC3 histone deacetylase 3 [ Homo sapiens ]
Synonyms : HDAC3; RPD3; HD3; RPD3-2; histone deacetylase 3; EC 3.5.1.98; SMAP45.
Gene ID : 8841
mRNA Refseq : NM_003883
Protein Refseq : NP_003874
MIM : 605166
UniProt ID : O15379
Chromosome Location : 5q31
Pathway : Signalling by NGF
Function : DNA binding; histone deacetylase activity; hydrolase activity; transcription factor binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All HDAC3 Products

Required fields are marked with *

My Review for All HDAC3 Products

Required fields are marked with *

0

Inquiry Basket

cartIcon
logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends