Recombinant Human interferon regulatory factor 1, His-tagged
Cat.No. : | IRF1-25H |
Product Overview : | Recombinant Human Interferon Regulatory Factor-1 produced inE.Coliis a single, non-glycosylated, polypeptide chain containing 134 amino acids (1-114) with a His Tag of 20 aa, and having a molecular mass of 15 kDa. The IRF-1 is purified by proprietary chromatographic techniques. |
- Specification
- Gene Information
- Related Products
Cat. No. : | IRF1-25H |
Description : | IRF1, Interferon regulatory factor 1, is a member of the interferon regulatory transcription factor (IRF) family which regulates gene expression critical to immune response, hematopoiesis and proliferation. IRF-1 is a transcriptional activator for IFN-A, IFN-B, and IFN-G stimulated genes. IRF1 is also a tumor suppressor transcription factor inducing apoptosis of tumorigenic cell lines. |
Source : | Escherichia Coli. |
Amino Acid Sequence : | MGSSHHHHHH SSGLVPRGSH MPITRMRMRP WLEMQINSNQ IPGLIWINKE EMIFQIPWKHAAKHGWDINK DACLFRSWAI HTGRYKAGEK EPDPKTWKAN FRCAMNSLPD IEEVKDQSRN KGSSAVRVYR MLPP |
Physical Appearance : | Sterile Filtered colorless solution. |
Purity : | Greater than 90.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. |
Formulation : | 1 mg/ml in 20mM Tris pH-8 and 10% glycerol. |
Storage : | Liquid Interferon although stable at 10°Cfor 1 week, should be stored below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
Gene Name : | IRF1 interferon regulatory factor 1 [ Homo sapiens ] |
Synonyms : | IRF1; interferon regulatory factor 1; MAR; IRF-1; OTTHUMP00000198266; interferon regulatory factor-1 |
Gene ID : | 3659 |
mRNA Refseq : | NM_002198 |
Protein Refseq : | NP_002189 |
MIM : | 147575 |
UniProt ID : | P10914 |
Chromosome Location : | 5q23-q31 |
Function : | sequence-specific DNA binding; transcription factor activity |
Products Types
◆ Recombinant Protein | ||
Irf1-1063R | Recombinant Rat Irf1 Protein, His&SUMO-tagged | +Inquiry |
IRF1-5046H | Recombinant Human IRF1 Protein, GST-tagged | +Inquiry |
IRF1-3169H | Recombinant Human IRF1 Protein, His (Fc)-Avi-tagged | +Inquiry |
IRF1-2752R | Recombinant Rat IRF1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Irf1-3572M | Recombinant Mouse Irf1 Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
IRF1-5168HCL | Recombinant Human IRF1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionVariations in IRF1 impact the body's response to bacterial infections.
IRF1 may play a key role in the development of autoimmune diseases.
IRF1 is crucial in antiviral defenses, enhancing response to viral infections.
IRF1 activates immune response genes, especially interferon-responsive genes.
IRF1 acts as a tumor suppressor, inhibiting cancer cell growth.
IRF1 affects the development and function of T cells and NK cells.
IRF1 regulates inflammation and cytokine production.
Customer Reviews (3)
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Accurate protein structural characterization, a cornerstone of our studies.
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