Recombinant Human SNCA, A30P Mutant
Cat.No. : | SNCA-76H |
Product Overview : | A Parkinson's disease-related point mutant (A30P) of α-Synuclein. A30P Mutant of α-Synuclein was overexpressed inE.coliand the recombinant protein was purified to apparent homogeneity by taking advantage of the thermo solubility of the protein and by using conventional column chromatography techniques. |
Unit | |
Price | |
Qty |
- Specification
- Gene Information
- Related Products
Cat. No. : | SNCA-76H |
Description : | Alpha-synuclein also known as SNCA is a protein which in humans is encoded by the SNCA gene. An alpha-synuclein fragment, known as the non-Abeta component (NAC) of Alzheimer"s disease amyloid, originally found in an amyloid-enriched fraction, is shown to be a fragment of its precursor protein, NACP, by cloning of the full-length cDNA. Later, NACP turned out to be a human homologue of Torpedo synuclein. Therefore, NACP is also referred to as human alpha-synuclein. |
Source : | Escherichia Coli. |
Physical Appearance : | Sterile filtered clorless solution. |
Purity : | Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by reducing and non-reducing SDS-PAGE Coomassie. |
Formulation : | The protein (1mg/ml) contains 20mM Tris-HCl buffer (pH 7.5), 0.1M NaCl. |
Storage : | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). |
Gene Name : | SNCA synuclein, alpha (non A4 component of amyloid precursor) [ Homo sapiens ] |
Synonyms : | SNCA; synuclein, alpha (non A4 component of amyloid precursor); PD1; NACP; PARK1; PARK4; MGC110988; Non-A beta component of AD amyloid;Alpha-synuclein;Non-A4 component of amyloid precursor; OTTHUMP00000161559; OTTHUMP00000161561; non A-beta component of AD amyloid |
Gene ID : | 6622 |
mRNA Refseq : | NM_000345 |
Protein Refseq : | NP_000336 |
UniProt ID : | P37840 |
Chromosome Location : | 4q21.3-q22 |
MIM : | 163890 |
Pathway : | Alzheimer"s disease; Parkinson"s disease |
Function : | Hsp70 protein binding; alpha-tubulin binding; achidonic acid binding; calcium ion binding; caspase inhibitor activity; dynein binding; fatty acid binding; fatty acid binding; ferrous iron binding; histone binding; identical protein binding; kinesin binding; magnesium ion binding; magnesium ion binding; phospholipase inhibitor activity; tau protein binding; transferrin transmembrane transporter activity; zinc ion binding |
Products Types
◆ Recombinant Protein | ||
SNCA-02H | Recombinant Human SNCA Protein | +Inquiry |
Snca-1372R | Recombinant Rat Snca Protein, GST-tagged | +Inquiry |
SNCA-2744H | Recombinant Human SNCA protein(11-110 aa), C-His-tagged | +Inquiry |
Snca-5996M | Recombinant Mouse Snca Protein, Myc/DDK-tagged | +Inquiry |
SNCA-2710H | Recombinant Human SNCA Protein, His-tagged | +Inquiry |
◆ Native Protein | ||
SNCA-27341TH | Native Human SNCA | +Inquiry |
SNCA-27342TH | Native Human SNCA | +Inquiry |
SNCA-27345TH | Native Human SNCA | +Inquiry |
◆ Lysates | ||
SNCA-1634HCL | Recombinant Human SNCA 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket