Recombinant Human Synuclein, Beta

• Cat.No.: SNCB-84H
• Product Overview: Recombinant Human β-Synuclein produced inE.Coliis a single,non-glycosylated polypeptide chain having a molecular mass of 14,287 Dalton.The Recombinant Human β-Synuclein is purified by proprietary chromatographic techniques.

Specification

• Cat. No.: SNCB-84H
• Description: β-synuclein (amino acids 1-134), an acidic neuronal protein of 134 amino acids, is extremely heat-resistant. β-synucelin also has a chaperone-like activity. Recently, β-synuclein has been suggested to inhibit β-synuclein aggregation.
• Source: Escherichia Coli.
• Sequence: DVFMKGLSM AKEGVVAAAE KTKQGVTEAA EKTKEGVLYV GSKTREGVVQ GVASVAEKTK EQASHLGGAV FSGAGNIAAA TGLVKREEFP TDLKPEEVAQ EAAEEPLIEP LMEPEGESYEDP PQEEYQEY EPEA.
• Physical Appearance: Sterile filtered clorless solution.
• Purity: Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by reducing and non-reducing SDS-PAGE Coomassie.
• Formulation: The protein (1mg/ml) contains 20mM Tris-HCl buffer (pH 7.5), 0.1M NaCl and 1mM MgCl₂.
• Applications: •ELISA• Inhibition Assays• Western Blotting.
• Characterization: On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 51kDa.
• Activity: Not known.
• Storage: Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).

Gene Information

• Gene Name: SNCB synuclein, beta [ Homo sapiens ]
• Synonyms: SNCB; synuclein, beta; Beta-synuclein
• Gene ID: 6620
• mRNA Refseq: NM_001001502
• Protein Refseq: NP_001001502
• UniProt ID: Q16143
• Chromosome Location: 5q35
• MIM: 602569
• Function: phospholipase inhibitor activity