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Recombinant Human Troponin I Type 3 (Cardiac)

Cat.No. : TNNI3-220H
Product Overview : Recombinant Human TNI produced inE.Coliis a single, non-glycosylated, polypeptide chain. The TNI contains 165 amino acids and has a molecular mass of 24,016 Dalton. The TNI is purified by proprietary chromatographic techniques.
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  • Gene Information
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Cat. No. : TNNI3-220H
Description : Troponin I, cardiac muscle is a protein that in humans is encoded by the TNNI3 gene. Troponin I (TnI) is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle; see also TNNI1. The others are troponin T and troponin C.
Source : Escherichia Coli.
Physical Appearance : Sterile Filtered colorless liquid formulation.
Formulation : 3.53 mg/ml solution containing 6M Urea 50mM Tris PH 8.
Purity : Greater than 98.0% as determined by both: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Dimers And Aggregates : Less than 1% as determined by silver-stained SDS-PAGE gel analysis.
Endotoxin : Endotoxin is less than 0.1 ng/µg of rHuTNC.
Protein Content : Protein quantitation was carried out by using 0.25 - 5.0 mg/ml Bradford assay vs. BSA.
Stability : Lyophilized rHuTNI although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution rHuTNI should be stored at 4°Cbetween 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Gene Name : TNNI3 troponin I type 3 (cardiac) [ Homo sapiens ]
Synonyms : TNNI3; troponin I type 3 (cardiac); CMH7; RCM1; cTnI; CMD2A; TNNC1; MGC116817; TNNI3; troponin I, cardiac; Troponin I, cardiac muscle; Cardiac troponin I; familial hypertrophic cardiomyopathy 7
Gene ID : 7137
mRNA Refseq : NM_000363
Protein Refseq : NP_000354
MIM : 191044
UniProt ID : P19429
Chromosome Location : 19q13.4
Pathway : Hypertrophic cardiomyopathy (HCM); Muscle contraction; Cardiac muscle contraction
Function : actin binding; calcium-dependent protein binding; protein domain specific binding; protein kinase binding; troponin C binding; troponin T binding; calcium channel inhibitor activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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