Recombinant Human Cadherin 2, Type 1, N-cadherin (Neuronal)

• Cat.No.: CDH2-87H
• Product Overview: Recombinant Human Cadherin-N protein 741-907 a.a. expressed inE.coli,43 kDa.

Specification

• Cat. No.: CDH2-87H
• Description: Cadherins comprise a family of Ca+ dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. The classical cadherins, E-, N- and P-cadherin, consist of large extracellular domains characterized by a series of five homologous NH2 terminal repeats. The most distal of these cadherins is thought to be responsible for binding specificity, transmembrane domains and carboxy terminal intracellular domains.
• Source: E.coli
• Presentation: Recombinant Human Cadherin-N protein at 100µg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.
• Characterization: On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 43 kDa.
• Applications: •ELISA •Inhibition Assays •Western Blotting
• Storage: Store vial at -20°Cto -80°C. When stored at the recommended temperature, this protein is stable for 12 months.

Gene Information

• Gene Name: CDH2 cadherin 2, type 1, N-cadherin (neuronal) [ Homo sapiens ]
• Synonyms: CDH2; cadherin 2, type 1, N-cadherin (neuronal); CDHN; NCAD; CD325; CDw325; cadherin 2, type 1; N-cadherin 1; neural cadherin; cadherin 2, N-cadherin (neuronal); calcium-dependent adhesion protein, neuronal; 5` partial; N-cadherin; Cadherin-2;CD325 antigen
• Gene ID: 1000
• mRNA Refseq: NM_001792
• Protein Refseq: NP_001783
• MIM: 114020
• UniProt ID: P19022
• Chromosome Location: 18q12.1
• Pathway: Arrhythmogenic right ventricular cardiomyopathy (ARVC); Cell adhesion molecules (CAMs); Cell-cell adhesion systems
• Function: RPTP-like protein binding; beta-catenin binding; calcium ion binding; protein kinase binding; protein phosphatase binding