Recombinant Human Keratin 8

• Cat.No.: KRT8-144H
• Product Overview: Recombinant human Keratin 8 protein expressed in E.coli encodes full length amino acids and has a molecular mass of 78 kDa.

Specification

• Cat. No.: KRT8-144H
• Description: Keratin 8 belongs to the type B (basic) subfamily of high molecular weight keratins and exists in combination with keratin 18. Keratin 8 is primarily found in the non-squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibodies that recognize only cytokeratin polypeptides 8 and 18.
• Source: E.coli.
• Formulation: 5µg/50µl purified human Keratin 8 protein at 0.1mg/ml in 50mM Tris-Acetate pH-7.5, 1mM EDTA and 20% Glyecrol.
• Application And Suggested Dilutions: •ELISA •Inhibition Assays •Western Blotting.
• Characterization: On SDS-PAGE commassie blue staining gel, the purified recombinant protein shows a band of 78 kDa.
• Storage & Stability: Store vial at -20°Cto -80°C. When stored at the recommended temperature, this protein is stable for 12 months.
• Publication:
  Salivary auto-antibodies as noninvasive diagnostic markers of oral cavity squamous cell carcinoma. (2014)

Gene Information

• Gene Name: KRT8 keratin 8 [ Homo sapiens ]
• Synonyms: keratin 8; K8; KO; CK8; CYK8; K2C8; CARD2; KRT8; cytokeratin 8; keratin, type II cytoskeletal 8; CK-8; Cytokeratin-8; Keratin-8
• Gene ID: 3856
• mRNA Refseq: NM_002273
• Protein Refseq: NP_002264
• MIM: 148060
• UniProt ID: P05787
• Function: structural molecule activity; protein binding