| Cat. No. : |
CSF3R-164H |
| Description : |
Colony stimulating factor 3 receptor (granulocyte), also known as granulocyte colony-stimulating factor receptor and CD114 antigen, is a member of the cytokine receptor superfamily. Members of this family, which also includes the receptors for IL-2 to IL-7, GM-CSF, EPO, TPO and GH, are characterised by the presence of four conserved cysteine residues in their extracellular domains. |
| Source : |
Human 293 cells. |
| Amino Acid Sequence : |
ECGHISVSAPIVHLGDPITASCIIK QNCSHLDPEPQILWRLGAELQPGGR QQRLSDGTQESIITLPHLNHTQAFL SCCLNWGNSLQILDQVELRAGYPPA IPHNLSCLMNLTTSSLICQWEPGPE THLPTSFTLKSFKSRGNCQTQGDSI LDCVPKDGQSHCCIPRKHLLLYQNM GIWVQAENALGTSMSPQLCLDPMDV VKLEPPMLRTMDPSPEAAPPQAGCL QLCWEPWQPGLHINQKCELRHKPQR GEASWALVGPLPLEALQYELCGLLP ATAYTLQIRCIRWPLPGHWSDWSPS LELRTTERAPTVRLDTWWRQRQLDP RTVQLFWKPVPLEEDSGRIQGYVVS WRPSGQAGAILPLCNTTELSCTFHL PSEAQEVALVAYNSAGTSRPTPVVF SESRGPALTRLHAMARDPHSLWVGW EPPNPWPQGYVIEWGLGPPSASNSN KTWRMEQNGRATGFLLKENIRPFQL YEIIVTPLYQDTMGPSQHVYAYSQE MAPSHAPELHLKHIGKTWAQLEWVP EPPELGKSPLTHYTIFWTNAQNQSF SAILNASSRGFVLHGLEPASLYHIH LMAASQAGATNSTVLTLMTLTPRSS NTKVDKKVEPKSCDKTHTCPPCPAP ELLGGPSVFLFPPKPKDTLMISRTP EVTCVVVDVSHEDPEVKFNWYVDGV EVHNAKTKPREEQYNSTYRVVSVLT VLHQDWLNGKEYKCKVSNKALPAPI EKTISKAKGQPREPQVYTLPPSRDE LTKNQVSLTCLVKGFYPSDIAVEWE SNGQPENNYKTTPPVLDSDGSFFLY SKLTVDKSRWQQGNVFSCSVMHEAL HNHYTQKSLSLSPGK. |
| Molecular Mass : |
Under reducing conditions Colony stimulating factor 3 receptor – Fc Chimera migrates as a broad band between 100 and 130 kDa in SDS-PAGE due to post-translation modifications, in particular glycosylation. |
| pI : |
The unmodified Colony stimulating factor 3 receptor - Fc Chimera has a predicted pI of 6.6. |
| % Carbohydrate : |
Purified Colony stimulating factor 3 receptor - Fc Chimera consists of 5-30% carbohydrate by weight. |
| Glycosylation : |
Colony stimulating factor 3 receptor Fc Chimera contains N-linked oligosacch arides and may contain O-linked oligosaccharides. |
| Purity : |
>95%, as determined by SDS-PAGE and visualized by silver stain. |
| Formulation : |
When reconstituted in 0.5 ml sterile phosphate-buffered saline, the solution will contain 1% human serum albumin (HSA) and 10% trehalose. |
| Storage : |
Lyophilized products should be stored at 2 to 8°C. Following reconstitution short-term storage at 4°C is recommended, and longer-term storage of aliquots at -18 to -20°C. Repeated freeze thawing is not recommended. |
