Recombinant Human Interleukin 8
Cat.No. : | IL8-130H |
Product Overview : | Recombinant Human interleukin 8 encoding the human IL-8 protein sequence (containing the signal peptide sequence, and the mature IL-8 sequence) and was expressed in modifiedhuman 293 cells. |
- Specification
- Gene Information
- Related Products
Cat. No. : | IL8-130H |
Description : | IL-8 is a member of the chemokine family. Chemokines are small secreted molecules containing 4 conserved cysteine residues and 2 disulfide linkages. IL-8 is a member of the CXC family of chemokines and is also known as CXCL8. IL-8 is predominantly produced by monocytes, T cells, NK cells and neutrophils and its expression is induced by IL-1 and TNF, as well as bacterial and viral products. |
Source : | Human 293 cells. |
Amino Acid Sequence : | SAKELRCQCIKTYSKP FH PKFIK ELRV IESGPHCANTE IIVKLSDGRELC LDP KEN WVQR VVEKFLKRAENS. |
Molecular Mass : | IL-8 migrates as a band at approximately 6-8 kDa in SDS-PAGE. This compares with unmodified IL-8 that has a predicted molecular mass of 8.4 kDa. |
PI : | IL-8 has a predicted pI of 9.02. |
Purity : | >95%, as determined by SDS-PAGE and visualized by silver stain. |
Formulation : | When reconstituted in 0.5 ml sterile phosphate-buffered saline, the solution will contain 1% human serum albumin (HSA) and 10% trehalose. |
Reconstitution : | It is recommended that 0.5 ml of sterile phosphate-buffered saline be added to the vial. |
Storage : | Lyophilized products should be stored at 2 to 8°C. Following reconstitution short-term storage at 4°C is recommended, and longer-term storage of aliquots at -18 to -20°C. Repeated freeze thawing is not recommended. |
Gene Name : | IL8 interleukin 8 [ Homo sapiens ] |
Synonyms : | IL8; interleukin 8; CXCL8; GCP-1; GCP1; LECT; LUCT; LYNAP; MDNCF; MONAP; NAF; NAP-1; NAP1; T cell chemotactic factor; beta-thromboglobulin-like protein; chemokine (C-X-C motif) ligand 8; emoctakin; granulocyte chemotactic protein 1; lymphocyte-derived neutrophil-activating factor; monocyte-derived neutrophil chemotactic factor; neutrophil-activating peptide 1; small inducible cytokine subfamily B, member 8; K60; T-cell chemotactic factor; b-ENAP; Monocyte-derived neutrophil chemotactic factor; Monocyte-derived neutrophil-activating peptide; Neutrophil-activating protein 1 |
Gene ID : | 3576 |
mRNA Refseq : | NM_000584 |
Protein Refseq : | NP_000575 |
MIM : | 146930 |
UniProt ID : | P10145 |
Chromosome Location : | 4q13-q21 |
Pathway : | Cytokine-cytokine receptor interaction; Pathways in cancer; Toll-like receptor signaling pathway; Bladder cancer; Chemokine signaling pathway; Epithelial cell signaling in Helicobacter pylori infection; RIG-I-like receptor signaling pathway; Signaling by GPCR |
Function : | interleukin-4 receptor activity; cytokine activity; chemokine activity; protein binding |
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◆ Lysates | ||
IL8-3002HCL | Recombinant Human IL8 cell lysate | +Inquiry |
IL8-3004HCL | Recombinant Human IL8 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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