Recombinant Human Growth Differentiation Factor 10

• Cat.No.: GDF10-474H
• Product Overview: Recombinant GDF10 protein was expressed inE.coliand purified by using conventional chromatography techniques. MW = 12.5 kDa (111aa).

Specification

• Cat. No.: GDF10-474H
• Description: GDF10 (Growth differentiation factor 10) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. It is expressed in femur, brain, lung, skeletal, muscle, pancreas and testis, and it plays a role in head formation and may have multiple roles in skeletalmorphogenesis. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues.
• Source: E.coli.
• Form: Liquid. In 10 mM sodium citrate (pH 3.5) containing 10% glycerol.
• Purity: > 95% by SDS – PAGE.
• Concentration: 1 mg/ml (determined by Bradford assay).
• Sequences Of Amino Acids: MQWDEPRVCS RRYLKVDFAD IGWNEWIISP KSFDAYYCAG ACEFPMPKIV RPSNHATIQS IVRAVGIIPG IPEPCCVPDK MNSLGVLFLD ENRNVVLKVY PNMSVDTCAC R.
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: GDF10 growth differentiation factor 10 [ Homo sapiens ]
• Synonyms: GDF10; growth differentiation factor 10; BMP3B; BMP-3b;bone morphogenetic protein 3B; Bone morphogenetic protein 3b; Growth/differentiation factor 10; GDF-10; Bone-inducing protein
• Gene ID: 2662
• mRNA Refseq: NM_004962
• Protein Refseq: NP_004953
• MIM: 601361
• UniProt ID: P55107
• Chromosome Location: 10q11.22
• Function: cytokine activity; growth factor activity