Recombinant Human Riboflavin Kinase
Cat.No. : | RFK-107H |
Product Overview : | Recombinant riboflavin kinase was expressed inE.coliand purified by using conventional chromatography techniques. MW = 20.5 kDa (182 aa). |
- Specification
- Gene Information
- Related Products
Cat. No. : | RFK-107H |
Description : | Riboflavin kinase, also known as flavokinase, belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. It is an enzyme that catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin-mononucleotide (FMN). |
Source : | E.coli. |
Amino Acid Sequence : | MGSSHHHHHH SSGLVPRGSH MPRADCIMRH LPYFCRGQVV RGFGRGSKQL GIPTANFPEQ VVDNLPADIS TGIYYGWASV GSGDVHKMVV SIGWNPYYKN TKKSMETHIM HTFKEDFYGE ILNVAIVGYL RPEKNFDSLE SLISAIQGDI EEAKKRLELP EHLKIKEDNF FQVSKSKIMN GH. |
Form : | Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol. |
Purity : | > 90% by SDS – PAGE. |
Concentration : | 1.0 mg/ml (determined by Bradford assay). |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Gene Name : | RFK riboflavin kinase [ Homo sapiens ] |
Synonyms : | RFK; riboflavin kinase; RIFK; FLJ11149; RP11-422N19.2; flavokinase; 0610038L10Rik; ATP:riboflavin 5"-phosphotransferase; EC 2.7.1.26; Flavokinase |
Gene ID : | 55312 |
mRNA Refseq : | NM_018339 |
Protein Refseq : | NP_060809 |
MIM : | 613010 |
UniProt ID : | Q969G6 |
Chromosome Location : | 9q21.31 |
Pathway : | Metabolic pathways; Riboflavin metabolism; Metabolism of vitamins and cofact |
Function : | ATP binding; magnesium ion binding; nucleotide binding; riboflavin kinase activity; riboflavin kinase activity; transferase activity; zinc ion binding |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionYes, RFK protein modulation may hold potential for therapeutic intervention in diseases related to its deficiency or dysregulation.
RFK protein's involvement in cellular metabolism makes it relevant in fields such as oncology, neurology, and mitochondrial disorders.
Generally, riboflavin supplementation is considered safe; however, high doses might lead to minor side effects like diarrhea or urine discoloration.
Treatment primarily involves riboflavin supplementation, aiming to restore adequate levels of active FMN and address the underlying deficiency.
Understanding RFK protein variants or deficiencies helps in tailoring riboflavin supplementation and treatments for individuals with specific genetic profiles or conditions.
Customer Reviews (3)
Write a reviewI highly recommend the RFK protein for various experimental applications.
It has demonstrated outstanding performance in ELISA, providing reliable and precise results.
It has been invaluable in protein electron microscopy structure analysis, facilitating detailed investigations and yielding valuable insights.
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