Catalog # or name ...
Armenian Monoclonall antibody to Human CCL2.
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.
CHO expressed, recombinant mouse MCP-1.
#95% by SDS-PAGE
ELISA, Flow Cyt, WB, IHC-FoFrs
Preservative: 0.09% Sodium Azide. Constituents: PBS, pH 7.2
Store at +4oC.
Belongs to the intercrine beta (chemokine CC) family.
Processing at the N-terminus can regulate receptor and target cell selectivity. Deletion of the N-terminal residue converts it from an activator of basophil to an eosinophil chemoattractant.
Antigen Gene Information
CCL2 chemokine (C-C motif) ligand 2 [ Homo sapiens ]
CCL2; chemokine (C-C motif) ligand 2; SCYA2, small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig je); C-C motif chemokine 2; GDCF 2; HC11; MCAF; MCP 1; MCP1; MGC9434; monocyte chemoattractant protein 1; monocyte chemotactic and activating factor; monocyte chemotactic protein 1; homologous to mouse Sig je; monocyte secretory protein JE; small inducible cytokine subfamily A (Cys Cys); member 2; SMC CF; HSMCR30; C-C motif chemokine 2; CCL 2; CCL2; CCL2_HUMAN; Chemokine (C C motif) ligand 2; Chemokine (CC motif) ligand 2; Chemokine C C motif ligand 2; Chemokine CC Motif Ligand 2; GDCF 2; GDCF 2 HC11; GDCF2; GDCF2 HC11; HC11; JE; MCAF; MCP 1; MCP-1; MGC9434; Monocyte chemoattractant protein 1; Monocyte chemotactic and activating factor; Monocyte chemotactic protein 1; Monocyte chemotactic protein 1 homologous to mouse Sig JE; Monocyte secretory protein JE; SCYA2; Small inducible cytokine A2 (monocyte chemotactic protein 1 homologous to mouse Sig JE); Small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig je); Small inducible cytokine A2; Small inducible cytokine A2 precursor; Small inducible cytokine subfamily A (Cys Cys), member 2; Small inducible cytokine subfamily A (CysCys) member 2; Small inducible cytokine subfamily A Cys Cys member 2; Small-inducible cytokine A2; SMC CF; SMCCF; Smooth muscle cell chemotactic factor; OTTHUMP00000163799; small-inducible cytokine A2; monocyte chemoattractant protein-1; small induci; MCP-1; SCYA2; GDCF-2; SMC-CF; HSMCR30;
Chagas disease (American trypanosomiasis), organism-specific biosystem; Chagas disease (American trypanosomiasis), conserved biosystem; Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem;
CCR2 chemokine receptor binding; CCR2 chemokine receptor binding; G-protein coupled receptor binding; chemokine activity; heparin binding;
45-16 Ramsey Road, Shirley, NY 11967, USA | TEL:1-631-559-9269 FAX:1-631-938-8127 | EMAIL:email@example.com
Copyright 2013 (c) Creative Biomart. All rights reserved. et: 187.50 ms