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Cat.No.
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CABT-38179MH
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Product Overview
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Mouse Monoclonall antibody to Human SLC2A1.
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Antigen Description
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This gene encodes a major glucose transporter in the mammalian blood-brain barrier. Mutations in this gene have been found in a family with paroxysmal exertion-induced dyskinesia.
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Isotype
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IgG1
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Immunogen
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Synthetic peptide derived from C-terminal of human Glucose Transporter GLUT1 protein.
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Host
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Mouse
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Species
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Human
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Specificity
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Expressed at variable levels in many human tissues.
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Formulation
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Liquid
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Applications
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IHC-P
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Storage buffer
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Preservative: 0.1% Sodium Azide. Constituents: 1% BSA, 50mM Tris, pH 7.6
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Storage
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Store at +4oC.
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Sequence similarities
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Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
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Post-translation modifications
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Phosphorylated upon DNA damage, probably by ATM or ATR.
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Antigen Gene Information
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Gene Name
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SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 [ Homo sapiens ]
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Official Symbol
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SLC2A1
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Synonyms
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SLC2A1; solute carrier family 2 (facilitated glucose transporter), member 1; GLUT, GLUT1; solute carrier family 2, facilitated glucose transporter member 1; DYT18; erythrocyte/brain; facilitated glucose transporter member 1; DYT17; DYT18; Erythrocyte/brain HepG2 glucose transporter; Erythrocyte/hepatoma glucose transporter; Glucose transporter 1; Glucose transporter type 1; Glucose transporter type 1 erythrocyte/brain; Glucose transporter type 1, erythrocyte/brain; GLUT; GLUT-1; GLUT1; GLUT1DS; GLUTB; GT1; GTG1; Gtg3; GTR1_HUMAN; HepG2 glucose transporter; MGC141895; MGC141896; PED; RATGTG1; SLC2A 1; SLC2A1; Solute carrier family 2 (facilitated glucose transporter), member 1; Solute carrier family 2; Solute carrier family 2 facilitated glucose transporter member 1; GLUT-1; OTTHUMP00000009006; hepG2 glucose transporter; glucose transporter type 1, erythrocyte/brain; PED; GLUT; DYT17; GLUT1; GLUT1DS;
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GeneID
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6513
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mRNA Refseq
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NM_006516
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Protein Refseq
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NP_006507
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MIM
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138140
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Uniprot ID
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P11166
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Chromosome Location
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1p34.2
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Pathway
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Adipocytokine signaling pathway, organism-specific biosystem; Adipocytokine signaling pathway, conserved biosystem; Bile secretion, organism-specific biosystem; Bile secretion, conserved biosystem; Facilitative Na+-independent glucose transporters, organism-specific biosystem;
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Function
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D-glucose transmembrane transporter activity; dehydroascorbic acid transporter activity; glucose transmembrane transporter activity; identical protein binding; kinase binding;
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Download Datasheet:
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