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Recombinant Human Prokineticin-2

Cat.No. : PROK2-464H
Product Overview : Recombinant human prokineticin-2 is an 8.8 kDa protein consisting of 81 amino acid residues and ten cysteine residues that potentially form five pairs of intra-molecular disulfide bonds. PROK2 was expressed inE. coli.
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Cat. No. : PROK2-464H
Description : Prokineticin-2 (PK2) is a cysteine-rich secreted protein that is expressed in the testis and in lower levels of the small intestine. PK2 regulates various biological functions including gastrointestinal motility, angiogenesis and circadiam rhythms. It is closely related to EG-VEGF (Prokineticin-1) and binds to two orphan B-protein-coupled receptors termed PK-R1 and PK-R2.
AA Sequence : AVITGACDKD SQCGGGMCCA VSIWVKSIRI CTPMGKLGDS CHPLTRKVPF FGRRMHHTC PCLPGLACLR TSFNRFICLA QK
Source : Escherichia Coli.
Supplied : Lyophilized powder from with no additives.
Purity : >98% by SDS-Page and HPLC analysis. Endotoxin level is less than 0.1ng per ug (1EU/ug) of protein.
Reconstitution : Lyophilized material should be reconstituted in water to a concentration of 0.1-1mg/ml. Allow to set at least 30 minutes at 4°C, mix well. If desired, tighten cap and centrifuge for 1 minute at 1000rpm to concentrate material in vial. This solution can be diluted into other buffered solutions or stored at 4°Cfor up to 1 week or at -20°Cfor future use. Note:If this material is not to be used for coating or labeling (or other applications requiring carrier free material), the addition of 0.1% BSA or HSA to dilution buffers or dilution in sterile culture media is recommended to enhance stability and minimize absorption to vial. Ideally, maintain stock >20ug/ml.
Storage : The lyophilized powder is stable at room temperature for a few weeks but it is best stored desiccated at -20℃. Reconstituted Prokineticin-2 should be stored in working aliquots at -20°C.
Gene Name : PROK2 prokineticin 2 [ Homo sapiens ]
Synonyms : BV8; PK2; KAL4; MIT1; PROK2; prokineticin 2; protein Bv8 homolog
Gene ID : 60675
mRNA Refseq : NM_001126128
Protein Refseq : NP_001119600
MIM : 146110
UniProt ID : Q9HC23
Function : G-protein-coupled receptor binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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Is PROK2 expression associated with disease development stage? 03/01/2022

The expression of PROK2 may be related to the stage of the disease, and the expression level of PROK2 may change at different stages of disease development.

How can PROK2 levels be regulated through diet or medications? 01/07/2022

There is no conclusive evidence that diet or medications can modulate PROK2 levels. However, some studies have shown that consuming antioxidant-rich foods may help reduce PROK2 activity.

How can I study the interaction of PROK2 with other genes or proteins? 12/22/2021

The interaction of PROK2 with other genes or proteins can be studied by using a combination of various experimental methods and techniques, such as yeast two-hybridization, co-immunoprecipitation, fluorescence resonance energy transfer, etc.

Is PROK2 related to other genes? 04/15/2021

PROK2 is associated with other genes in a complex manner, and may interact with multiple genes and participate in a variety of biochemical processes.

What are the mutation types of PROK2? 10/19/2020

The types of mutations in PROK2 include point mutations, insertions/deletions, duplications, etc., which may cause structural and functional abnormalities of the protein.

How to use the expression pattern of PROK2 for disease diagnosis? 03/22/2020

By detecting the expression pattern of PROK2, it can assist in the diagnosis of certain diseases, such as cancer, neurodegenerative diseases, etc.

Customer Reviews (3)

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Reviews
12/31/2021

    The impurities are not obvious, clear and transparent, and the purity is high.

    09/07/2021

      PROK2 has high structural stability.

      06/28/2021

        PROK2 has excellent compatibility in vivo.

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