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Cat.No.
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CABT-38799RH
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Product Overview
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Rabbit Monoclonall antibody to Human TMPRSS6.
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Antigen Description
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The protein encoded by this gene is a type II transmembrane serine proteinase that is found attached to the cell surface. The encoded protein may be involved in matrix remodeling processes in the liver.
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Isotype
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IgG
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Immunogen
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Synthetic peptide, corresponding to a region within N-terminal amino acids 71-120 (LLWYFLGYKA EVMVSQVYSG SLRVLNRHFS QDLTRRESSA FRSETAKAQK) of Human Matriptase 2 .
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Host
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Rabbit
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Species
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Human
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Specificity
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Liver specific.
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Clone
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FQ2052Z
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Formulation
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Liquid
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Purity Detail
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Immunogen affinity purified
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Applications
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WB
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Storage buffer
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Preservative: None. Constituents: 2% Sucrose, PBS
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Storage
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Shipped at 4oC. Upon delivery aliquot and store at -20oC. Avoid freeze / thaw cycles.
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Sequence similarities
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Belongs to the peptidase S1 family.Contains 2 CUB domains.Contains 3 LDL-receptor class A domains.Contains 1 peptidase S1 domain.
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Antigen Gene Information
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Gene Name
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TMPRSS6 transmembrane protease, serine 6 [ Homo sapiens ]
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Official Symbol
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TMPRSS6
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Synonyms
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TMPRSS6; transmembrane protease, serine 6; transmembrane protease serine 6; FLJ30744; Matriptase-2; Membrane type serine proteinase 2; MTSP 2; MTSP2; PVAE354; TMPRSS 6; TMPRSS6; TMPS6_HUMAN; TMSP 6; TMSP6; Transmembrane protease serine 6; Type II Membrane Serine Proteinase 6; matriptase-2; type II transmembrane serine protease 6; membrane-bound mosaic serine proteinase matriptase-2; IRIDA;
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GeneID
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164656
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mRNA Refseq
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NM_153609
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Protein Refseq
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NP_705837
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MIM
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609862
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Uniprot ID
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Q8IU80
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Chromosome Location
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22q13.1
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Function
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peptidase activity; serine-type endopeptidase activity;
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Download Datasheet:
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