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Recombinant Human AZU1 protein, His-tagged

Cat.No. : AZU1-588H
Product Overview : Recombinant Human AZU1 (Ile27-Pro250) protein was fused to His-tag at C-terminus and expressed in human 293 cells (HEK293).
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Description : Azurocidin (AZU1) is also known as Heparin-binding protein (HBP), Cationic antimicrobial protein CAP37, is a neutrophil granule-derived antibacterial and monocyte- and fibroblast-specific chemotactic glycoprotein. which belongs to the peptidase S1 family and elastase subfamily. AZU1/HBP contains 1 peptidase S1 domain. AZU1 binds heparin. The cytotoxic action of AZU1 is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. AZU1 may play a role in mediating recruitment of monocytes in the second wave of inflammation.
Source : HEK293
Species : Human
Tag : His
Predicted N Terminal : Ile27
Form : Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 10% trehalose.
Molecular Mass : The protein has a calculated MW of 25.0 kDa. The protein migrates as 34-42 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Protein length : Ile27-Pro250
Endotoxin : Less than 1.0 EU per μg by the LAL method.
Purity : >95% as determined by SDS-PAGE.
Storage : For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20 to -70 centigrade for 12 months in lyophilized state;
-70 centigrade for 3 months under sterile conditions after reconstitution.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Name : AZU1
Official Symbol : AZU1
Synonyms : AZU1; azurocidin 1; azurocidin; AZAMP; AZU; CAP37; cationic antimicrobial protein 37; HBP; heparin binding protein; HUMAZUR; NAZC; neutrophil azurocidin; heparin-binding protein; cationic antimicrobial protein CAP37
Gene ID : 566
mRNA Refseq : NM_001700
Protein Refseq : NP_001691
MIM : 162815
UniProt ID : P20160

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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