Recombinant Human PVRL2 protein, Fc-tagged
Cat.No. : | PVRL2-608H |
Product Overview : | Recombinant Human PVRL2 (Gln32-Leu360) protein was fused to human IgG1 Fc tag at C-terminus and expressed in human 293 cells (HEK293). |
- Specification
- Gene Information
- Related Products
Description : | Poliovirus receptor-related 2 (PVRL2) is also known as nectin-2 and CD112 (formerly herpesvirus entry mediator B, HVEB), which is a human plasma membrane glycoprotein. PVRL2 is one of the plasma membrane components of adherens junctions. PVRL2 also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in PVRL2 gene have been associated with differences in the severity of multiple sclerosis. Also, PVRL2 binds with low affinity to TIGIT. Furthermore, PVRL2 acts as a receptor for herpes simplex virus 1 (HHV-1) mutant Rid1, herpes simplex virus 1 (HHV-2) and pseudorabies virus (PRV). |
Source : | HEK293 |
Species : | Human |
Tag : | human IgG1 Fc |
Predicted N Terminal : | Gln32 |
Form : | Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 62.2 kDa. The protein migrates as 70-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein length : | Gln32-Leu360 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | PVRL2 |
Official Symbol : | PVRL2 |
Synonyms : | PVRL2; poliovirus receptor-related 2 (herpesvirus entry mediator B); HVEB; poliovirus receptor-related protein 2; CD112; PRR2; PVRR2; nectin-2; poliovirus receptor-like 2; herpesvirus entry protein B |
Gene ID : | 5819 |
mRNA Refseq : | NM_001042724 |
Protein Refseq : | NP_001036189 |
MIM : | 600798 |
UniProt ID : | Q92692 |
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◆ Recombinant Protein | ||
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PVRL2-611H | Active Recombinant Human PVRL2 Protein, Fc-Avi-tagged, Biotinylated | +Inquiry |
PVRL2-3715R | Recombinant Rhesus monkey PVRL2 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
PVRL2-3010HCL | Recombinant Human PVRL2 cell lysate | +Inquiry |
PVRL2-2647MCL | Recombinant Mouse PVRL2 cell lysate | +Inquiry |
PVRL2-1403RCL | Recombinant Rat PVRL2 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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