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Recombinant Human CD209 protein, hFc-tagged

Cat.No. : CD209-633H
Product Overview : Recombinant Human CD209 protein(NP_066978.1)(Lys62-Ala404), fused with hFc tag, was expressed in HEK293.
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Source : HEK293
Species : Human
Tag : hFc
Form : Lyophilized from sterile PBS, pH 7.4Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Molecular Mass : The recombinant human Fc/DC-SIGN chimera is a disulfide-linked homodimeric protein. The reduced monomer consists of 580 amino acids and has a calculated molecular mass of 65.8 kDa. As a result of glycosylation, the apparent molecular mass of rh Fc/DC-SIGN is approximately 75 kDa in SDS-PAGE under reducing conditions.
Proteinlength : Lys62-Ala404
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method
Purity : > 97 % as determined by SDS-PAGE
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : CD209 CD209 molecule [ Homo sapiens ]
Official Symbol : CD209
Synonyms : CD209; CD209 molecule; CD209 antigen; CDSIGN; CLEC4L; DC SIGN; DC SIGN1; HIV gpl20-binding protein; C-type lectin domain family 4 member L; C-type lectin domain family 4, member L; dendritic cell-specific ICAM-3-grabbing non-integrin 1; dendritic cell-specific intracellular adhesion molecules (ICAM)-3 grabbing non-integrin; DC-SIGN; DC-SIGN1; MGC129965;
Gene ID : 30835
mRNA Refseq : NM_001144893
Protein Refseq : NP_001138365
MIM : 604672
UniProt ID : Q9NNX6

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can you discuss the role of CD209 in shaping adaptive immune responses and its impact on immunotherapy strategies? 01/23/2021

CD209 influences adaptive immune responses by modulating dendritic cell-T cell interactions. Understanding its role is critical for optimizing immunotherapy approaches, particularly in vaccine development.

How does CD209 participate in the recognition of glycosylated pathogens, and what are the implications for innate immunity? 11/14/2019

CD209 recognizes glycosylated patterns on pathogens, particularly through interactions with high-mannose structures. This recognition is crucial for initiating innate immune responses.

Can you elaborate on the genetic polymorphisms of CD209 and their association with susceptibility to infectious diseases? 06/09/2019

Genetic polymorphisms in CD209 have been associated with susceptibility to infectious diseases, including tuberculosis and HIV, suggesting a role in modulating host-pathogen interactions.

How does CD209 contribute to the formation of immunological synapses between dendritic cells and T cells, and what molecular events are involved? 02/09/2019

CD209 facilitates immunological synapse formation by mediating adhesion between dendritic cells and T cells. Molecular events involve interactions with ICAM-3 and other adhesion molecules.

How does CD209 contribute to immune responses, particularly in the context of antigen presentation? 06/02/2018

CD209 facilitates antigen capture by dendritic cells and modulates immune responses by mediating the interaction between dendritic cells and T cells during antigen presentation.

Customer Reviews (3)

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01/07/2021

    The team promptly addressed my inquiries and provided valuable assistance in selecting the right recombined protein for our research.

    12/23/2019

      This product consistently delivers accurate results in our experiments.

      09/14/2018

        Quick service! The team provided efficient assistance in choosing the right protein for us.

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