Mouse Anti-Human ALPP Monoclonal Antibody, PLAP

Cat.No.

CABT-26830MH

Product Overview

Mouse monoclonal antibody to Human ALPP.

Antigen Description

There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. The coding sequence for this form of alkaline phosphatase is unique in that the 3 untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized.

Clone

9C7

Isotype

IgG2a

Conjugation

PLAP

Immunogen

HEp-2 cells with boosted surface expression of PLAP

Host

Mouse

Species

Human

Specificity

Human placental alkaline phosphatase, Regan and Nagao isoenzymes. No cross reaction with other isoenzymes of AP.

Formulation

Liquid

Concentration

Batch dependent within range:0.70 -1.40 mg/ml

Purity Detail

Protein A purified

Applications

ELISA, IHC-Fr, IHC-P, RIA

Storage buffer

Preservative: NoneConstituents: PBS

Storage

Store at +4^oC short term (1-2 weeks). Aliquot and store at -20^oC or -80^oC. Avoid repeated freeze / thaw cycles.

Sequence similarities

Belongs to the alkaline phosphatase family.

Light chain type

kappa

Antigen Gene Information