Recombinant Rat Gpt, His tagged
Cat.No. : | Gpt-294R |
Product Overview : | Recombinant Rat Gpt (NP_112301.1) (Met 1-Ser 496), fused with a C-terminal polyhistidine tag, was produced in Baculovirus-Insect cells. |
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Source : | Baculovirus-Insect Cells |
Species : | Rat |
Tag : | His |
Form : | Lyophilized from sterile 50mM Tris, 100mM NaCl, pH 8.0, 10% glycerol, 0.5mM TCEP |
Molecular Mass : | The recombinant rat Gpt1 comprises 506 amino acids with a predicted molecular mass of 55 kDa. It migrates as an approximately 48 kDa band in reduced SDS-PAGE. |
Endotoxin : | < 1.0 eu per μg of the protein as determined by the LAL method. |
Stability : | Samples are stable for up to twelve months from date of receipt at -70oC. |
Storage : | Store it under sterile conditions at -20oC~-70oC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Publication : |
Liver enzyme delayed clearance in rat treated by CSF1 receptor specific antagonist Sotuletinib (2021)
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Gene Name : | Gpt glutamic-pyruvate transaminase (alanine aminotransferase) [ Rattus norvegicus ] |
Official Symbol : | Gpt |
Gene ID : | 81670 |
mRNA Refseq : | NM_031039 |
Protein Refseq : | NP_112301 |
Products Types
◆ Recombinant Protein | ||
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GPT-5304H | Recombinant Human GPT Protein, GST-tagged | +Inquiry |
GPT-2236H | Recombinant Human GPT Protein, MYC/DDK-tagged | +Inquiry |
◆ Native Protein | ||
GPT-187H | Active Native Human Glutamate Pyruvate Transaminase | +Inquiry |
GPT-188S | Active Native Swine Glutamate Pyruvate Transaminase | +Inquiry |
GPT-5344H | Native Human Glutamic-Pyruvate Transaminase (alanine aminotransferase) | +Inquiry |
◆ Lysates | ||
GPT-721RCL | Recombinant Rat GPT cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionThe GPT gene, encompassing GPT1 and GPT2, is pivotal in glucose and amino acid metabolism. GPT2 is notably linked to tumorigenesis in various cancers, while the involvement of GPT1 in cancer remains uncertain and requires further exploration.
The GPT gene encodes ALT1, a key enzyme in cellular metabolism. ALT1 facilitates the reversible transamination between alanine and 2-oxoglutarate, crucial for glucose and amino acid metabolism. Elevated serum ALT1 levels are commonly used as a biomarker for liver injury caused by drug toxicity, infection, alcohol, and steatosis.
SMS protein alone doesn't impact LSCC patient prognosis, but when combined with GPT, it shows significance. Inconsistency between SMS transcriptional and protein levels may stem from various factors, including the involvement of regulatory elements and different post-transcriptional and post-translational modifications.
Analysis of LSCC tissues and cell lines revealed an inverse relationship between GPT and SMS expressions, confirmed through qRT-PCR and TCGA data. GPT protein, primarily located in the epithelium, was down-regulated in LSCC tissues.
GPT gene expression serves as a marker for cancer-induced metabolic reprogramming in tissues, indicating shifts in energy metabolism and biosynthetic processes.
Customer Reviews (3)
Write a reviewFantastic customer support. They genuinely care about the success of our research.
Top-notch protein quality! It's our go-to for reliable and reproducible results.
Very happy with this lab product!
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