Active Recombinant Human HMGB1 protein(Met1-Glu215), hFc-tagged
Cat.No. : | HMGB1-752H |
Product Overview : | Recombinant Human HMGB1 protein (NP_002119.1) (Met 1-Glu 215) was expressed in HEK293 with the fused Fc region of Human IgG1 at the N-terminus. |
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Source : | HEK293 |
Species : | Human |
Tag : | N-hFc |
Protein length : | Met1-Glu215 |
Form : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Bio-activity : | Measured by its binding ability in a functional ELISA. Immobilized recombinant mouse AGER at 2 μg/ml (100 μl/well) can bind human HMGB1. The EC50 of human HMGB1 is 0.23 μg/ml. |
Molecular Mass : | The recombinant human HMGB1/Fc is a disulfide-linked homodimeric protein.The reduced monomer consists of 452 amino acids and has a predictedmolecular mass of 51.5 kDa. As a result of glycosylation, the apparent molecular mass of rhHMGB1/Fc monomer is approximately 55-60 kDa inSDS-PAGE under reducing conditions. |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Purity : | > 97 % as determined by SDS-PAGE |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | HMGB1 high mobility group box 1 [ Homo sapiens ] |
Official Symbol : | HMGB1 |
Synonyms : | HMGB1; high mobility group box 1; high mobility group (nonhistone chromosomal) protein 1 , high mobility group box 1 , HMG1; high mobility group protein B1; Amphoterin; DKFZp686A04236; high mobility group protein 1; HMG3; SBP 1; Sulfoglucuronyl carbohydrate binding protein; HMG-1; high-mobility group box 1; high-mobility group (nonhistone chromosomal) protein 1; HMG1; SBP-1; |
Gene ID : | 3146 |
mRNA Refseq : | NM_002128 |
Protein Refseq : | NP_002119 |
MIM : | 163905 |
UniProt ID : | P09429 |
Products Types
◆ Native Protein | ||
HMGB1-8447B | Active Native Bovine HMGB1 | +Inquiry |
◆ Lysates | ||
HMGB1-2076HCL | Recombinant Human HMGB1 cell lysate | +Inquiry |
HMGB1-1677MCL | Recombinant Mouse HMGB1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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