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Recombinant Human HPX, His tagged

Cat.No. : HPX-754H
Product Overview : Recombinant Human HPX (NP_000604.1) (Met 1-His 462), fused with a C-terminal polyhistidine tag, was produced in Human Cell.
  • Specification
  • Gene Information
  • Related Products
Source : Human Cells
Species : Human
Tag : His
Form : Lyophilized from sterile PBS, pH 7.4
Molecular Mass : The secreted recombinant human HPX comprises 450 amino acids with a predicted molecular mass of 50.7 kDa. As a result of glycosylation, rhHPX migrates as an approximately 70-75 kDa band in SDS-PAGE under reducing conditions.
Endotoxin : < 1.0 eu per μg of the protein as determined by the LAL method.
Stability : Samples are stable for up to twelve months from date of receipt at -70oC.
Storage : Store it under sterile conditions at -20oC~-70oC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Name : HPX hemopexin [ Homo sapiens ]
Official Symbol : HPX
Gene ID : 3263
mRNA Refseq : NM_000613
Protein Refseq : NP_000604
MIM : 142290
UniProt ID : P02790

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can HPX be used as a diagnostic marker for hemolytic disorders? 03/08/2022

Yes, low levels of HPX in the blood can be an indicator of hemolytic disorders.

How is HPX involved in managing heme in the body? 10/27/2021

HPX binds to free heme released from hemoglobin, preventing its toxic effects and aiding in its clearance.

How does HPX contribute to the prevention of heme-related toxicity? 04/07/2021

HPX binds to heme, preventing its oxidative and inflammatory damage to tissues and organs.

What clinical conditions are associated with heme release, making HPX relevant? 06/10/2018

Hemolysis, hemoglobinopathies, and various types of anemias can lead to heme release, highlighting the clinical relevance of HPX.

How is HPX regulated in the body, and can its levels be influenced by medications? 12/16/2017

HPX levels can be influenced by various factors, including inflammation and medications like glucocorticoids.

Customer Reviews (3)

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Reviews
12/09/2019

    the manufacturer offers a wide range of HPX protein variants, including recombinant or native forms, as well as different conjugates and modifications.

    02/02/2018

      As a researcher using HPX protein, I have found numerous advantages in its application during trials for various experimental purposes.

      08/15/2017

        the HPX protein is known for its strong affinity for phospholipids, particularly phosphatidylserine (PS), on the outer leaflet of cell membranes.

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