Rabbit Anti-Human CTCFL Monoclonal Antibody

Cat.No.

CABT-27522RH

Product Overview

Rabbit monoclonal antibody to Human CTCFL.

Antigen Description

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus belongs to receptor type PTP. This gene is specifically expressed in hematopoietic cells. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Four alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported.

Isotype

IgG

Immunogen

Synthetic peptide derived from within residues 1 - 100 of Human BORIS.

Host

Rabbit

Species

Human

Formulation

Liquid

Concentration

0.200 mg/ml

Purity Detail

Immunogen affinity purified

Applications

ChIP, ICC/IF, IHC-P, WB

Storage buffer

Preservative: 0.02% Sodium AzideConstituents: 1% BSA, PBS, pH 7.4

Storage

Store at +4^oC short term (1-2 weeks). Aliquot and store at -20^oC or -80^oC. Avoid repeated freeze / thaw cycles.

Sequence similarities

Belongs to the CTCF zinc-finger protein family.Contains 11 C2H2-type zinc fingers.

Antigen Gene Information