Catalog # or name ...
Rabbit monoclonal antibody to Human CTCFL.
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus belongs to receptor type PTP. This gene is specifically expressed in hematopoietic cells. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Four alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported.
Synthetic peptide derived from within residues 1 - 100 of Human BORIS.
Immunogen affinity purified
ChIP, ICC/IF, IHC-P, WB
Preservative: 0.02% Sodium AzideConstituents: 1% BSA, PBS, pH 7.4
Store at +4oC short term (1-2 weeks). Aliquot and store at -20oC or -80oC. Avoid repeated freeze / thaw cycles.
Belongs to the CTCF zinc-finger protein family.Contains 11 C2H2-type zinc fingers.
Antigen Gene Information
CTCFL CCCTC-binding factor (zinc finger protein)-like [ Homo sapiens ]
CTCFL; CCCTC-binding factor (zinc finger protein)-like; transcriptional repressor CTCFL; BORIS; cancer/testis antigen 27; CT27; dJ579F20.2; BORIS like protein; Brother of the regulator of imprinted sites; Cancer/testis antigen 27; CCCTC binding factor (zinc finger protein) like; CCCTC-binding factor; CT27; CTCF paralog; CTCF T; CTCF-like protein; CTCFL; CTCFL_HUMAN; dJ579F20.2; HMG 1L1; HMGB1L1; MGC163358; MGC169105; MGC169106; Putative high mobility group protein 1 like 1; Putative high mobility group protein B1 like 1; Transcriptional repressor CTCFL; Zinc finger protein CTCF-T; HMG-1L1; CTCF paralog; CTCF-like protein; BORIS-like protein; OTTHUMP00000031376; OTTHUMP00000174287; zinc finger protein CTCF-T; brother of the regulator of imprinted sites; putative high mobility group pr; CTCF-T; HMGB1L1;
DNA binding; histone binding; metal ion binding; protein binding; sequence-specific DNA binding;
45-16 Ramsey Road, Shirley, NY 11967, USA | TEL:1-631-559-9269 FAX:1-631-938-8127 | EMAIL:email@example.com
Copyright 2013 (c) Creative Biomart. All rights reserved. et: 3,375.00 ms