Catalog # or name ...
Mouse monoclonal antibody to Human TPP1.
Members of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM 179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases (summary by Scherle et al., 1993
Recombinant fragment, corresponding to amino acids 195-305 of Human TPP1
Batch dependent within range:0.50 -1.00 mg/ml
Protein G purified
Preservative: NonePBS, pH 7.2
Shipped at 4oC. Upon delivery aliquot and store at -20oC or -80oC. Avoid repeated freeze / thaw cycles.
Belongs to the peptidase S53 family.
Light chain type
Antigen Gene Information
TPP1 tripeptidyl peptidase I [ Homo sapiens ]
TPP1; tripeptidyl peptidase I; ceroid lipofuscinosis, neuronal 2, late infantile (Jansky Bielschowsky disease) , CLN2; tripeptidyl-peptidase 1; TPP I; Cell growth inhibiting gene 1 protein; Cell growth-inhibiting gene 1 protein; Ceroid lipofuscinosis neuronal 2; Ceroid lipofuscinosis neuronal 2 late infantile (Jansky Bielschowsky disease); Ceroid lipofuscinosis neuronal 2 late infantile; CLN 2; CLN2; GIG 1; GIG1; Growth inhibiting protein 1; LPIC; Lysosomal pepstatin insensitive protease; Lysosomal pepstatin-insensitive protease; MGC21297; TPP 1; TPP I; TPP-1; TPP-I; Tpp1; TPP1_HUMAN; TPPI; Tripeptidyl aminopeptidase; Tripeptidyl peptidase I; Tripeptidyl-peptidase 1; Tripeptidyl-peptidase I; OTTHUMP00000164588; tripeptidyl aminopeptidase; growth-inhibiting protein 1; cell growth-inhibiting gene 1 protein; lysosomal pepstatin insensitive protease; CLN2; GIG1; LPIC; TPP-1;
Activation of Chaperones by IRE1alpha, organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Lysosome, organism-specific biosystem; Lysosome, conserved biosystem; Unfolded Protein Response, organism-specific biosystem;
endopeptidase activity; endopeptidase activity; metal ion binding; peptidase activity; peptide binding;
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