Recombinant Human ERBB2, His tagged

• Cat.No.: ERBB2-922H
• Product Overview: Recombinant Human ERBB2 extracellular domain (Met 1-Thr 652) (NP_004439.2), fused with the polyhistidine tag at the C-terminus, was produced in Human Cell.

Specification

• Source: Human Cells
• Species: Human
• Tag: His
• Form: Lyophilized from sterile PBS, pH 7.4
• Molecular Mass: The recombinant human ErbB2 comprises 641 amino acids and has a calculated molecular mass of 71 kDa. As a result of glycosylation, rh ErbB2 migrates as an approximately 100-110 kDa protein in SDS-PAGE under reducing conditions.
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Stability: Samples are stable for up to twelve months from date of receipt at -70oC.
• Storage: Store it under sterile conditions at -20oC~-70oC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4℃ before opening to recover the entire contents.
• Publication:
  The neonatal Fc receptor (FcRn) binds independently to both sites of the IgG homodimer with identical affinity (2015)
  In vitro Fab display: a cell-free system for IgG discovery (2014)
  Generating bispecific human IgG1 and IgG2 antibodies from any antibody pair. (2012)
  Peptidomimetic-based antibody surrogate for HER2 (2021)

Gene Information

• Gene Name: ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) [ Homo sapiens ]
• Official Symbol: ERBB2
• Gene ID: 2064
• mRNA Refseq: NM_001005862
• Protein Refseq: NP_001005862
• MIM: 164870
• UniProt ID: P04626