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Recombinant Mouse Cxcl5 protein

Cat.No. : Cxcl5-97M
Product Overview : Recombinant Mouse Cxcl5 protein (70 a.a.) was expressed in Escherichia coli.
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  • Gene Information
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Description : CXCL5 is a small cytokine belonging to the CXC chemokine family that is also known as epithelial-derived neutrophil-activating peptide 78 (ENA-78) and the gene for CXCL5 is encoded by the CXCL5 gene. It May participate in the recruitment of inflammatory cells by injured or infected tissue. CXCL5 is cleaved into the following 2 chains: GCP-2 (1-78) and GCP-2 (9-78) which attract neutrophils and are involved in neutrophil activation. Recombinant Mouse CXCL5 (92 a.a.) contains 92 amino acids and shares 57 % amino acid sequence identity with human CXCL5.
Source : E.coli
Species : Mouse
Form : Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH 7.4.
Bio-activity : Fully biologically active when compared to standard. The biological activity determined by a chemoattract bioassay using human neutrophils is in a concentration range of 10-100 ng/ml.
Molecular Mass : Approximately 7.6 kDa, a single non-glycosylated polypeptide chain containing 70 amino acids.
Protein length : 70
AA Sequence : TELRCVCLTVTPKINPKLIANLEVI PAGPQCPTVEVIAKLKNQKEVCLDP EAPVIKKIIQKILGSDKKKA
Endotoxin : Less than 0.1 EU/µg of rMuLIX, 70a.a./CXCL5 as determined by LAL method.
Purity : >96% by SDS-PAGE and HPLC analysis.
Storage : Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Reconstitution : We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤-20 centigrade. Further dilutions should be made in appropriate buffered solutions.
Gene Name : Cxcl5
Official Symbol : Cxcl5
Synonyms : CXCL5; chemokine (C-X-C motif) ligand 5; C-X-C motif chemokine 5; cytokine LIX; small-inducible cytokine B5; granulocyte chemotactic protein-2; small inducible cytokine B subfamily, member 5; small inducible cytokine subfamily B, member 15; LIX; GCP-2; Scyb5; Scyb6; ENA-78; AMCF-II;
Gene ID : 20311
mRNA Refseq : NM_009141
Protein Refseq : NP_033167
UniProt ID : P50228

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How does CXCL5 contribute to tumor progression and metastasis? 12/04/2021

CXCL5 is implicated in promoting tumor growth and metastasis by facilitating the migration of cancer cells and modulating the tumor microenvironment.

Are there any ongoing clinical trials targeting CXCL5 for therapeutic purposes? 05/15/2020

Several clinical trials are exploring the efficacy of drugs that modulate CXCL5 levels in various diseases, including cancer, autoimmune disorders, and inflammatory conditions.

In what ways does CXCL5 participate in the regulation of angiogenesis? 03/01/2019

CXCL5 has been identified as a regulator of angiogenesis, influencing the formation of new blood vessels, a process crucial for tumor growth and wound healing.

How can CXCL5 be harnessed for regenerative medicine purposes? 03/31/2018

CXCL5's role in recruiting cells to damaged tissues makes it a potential candidate for enhancing regenerative medicine approaches, such as tissue repair and wound healing.

In what ways can CXCL5 be used as a biomarker in clinical diagnostics? 03/19/2016

CXCL5 levels can be measured in blood or tissue samples to assess the extent of inflammation, aiding in the diagnosis and monitoring of various diseases.

Customer Reviews (3)

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Reviews
06/25/2021

    Its versatility and reliability make it an indispensable asset for scientists seeking to explore the complexities of various biological systems.

    01/13/2021

      Its stability and functional attributes ensure reliable imaging and facilitate the elucidation of complex protein structures.

      03/28/2018

        The CXCL5 protein is known for its exceptional quality, making it a highly suitable choice for meeting diverse experimental needs.

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