| Cat. No. : |
IL17D-167H |
| Description : |
The originally described IL-17 protein, now known as IL-17A, is a homodimer of two 155 amino acid chains, secreted by activated T-cells and acts on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules. Today, IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region and differ from one another in their N-terminal segments and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as disulfide-linked homodimers. IL-17D has the ability to stimulate the production of IL-6, IL-8 and GM-CSF and inhibits hemopoiesis of myeloid progenitor cells in colony forming assays. |
| Source : |
E.coli. |
| Purity : |
> 98% by SDS-PAGE and HPLC analysis. |
| Endotoxin Level : |
< 0.1 ng per ug of IL-17D. |
| Stabilizer : |
None. |
| Formulation : |
Lyophilized. |
| Biological Activity : |
Testing in progress. |
| Reconstitution : |
The human IL-17D should be reconstituted in water to a concentration of 0.1-1.0 mg/ml. This solution can be diluted in water or other buffer solutions or stored at -20℃. |
| Stability : |
The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20℃. Reconstituted human IL-17D should be stored in working aliquots at -20℃. Avoid repeated freeze-thaw cycles. |
