Mu-crystallin homolog
Cat.No. : | CBCRY14 |
- Specification
- Gene Information
- Related Products
Cat. No. : | CBCRY14 |
Background : | Crystallins are separated into two classes: taxon-specific and ubiquitous. The former class is also called phylogenetically-restricted crystallins. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. This gene encodes a taxon-specific crystallin protein that binds NADPH and has sequence similarity to bacterial ornithine cyclodeaminases. The encoded protein does not perform a structural role in lens tissue, and instead it binds thyroid hormone for possible regulatory or developmental roles. Multiple alternatively spliced transcript variants have been found for this gene. |
Protein Classification : | Oxidoreductase |
Structure Weight : | 68589.65 Da |
Polymer : | 1 |
Molecule : | Mu-crystallin homolog |
Chain Length : | 312 amino acids |
PDB ID : | 2I99 |
MMDB ID : | 44495 |
Source : | E.coli |
Method : | X-Ray Diffraction |
Resolution : | 2.6Å |
Ligand Chemical Component : | NAD |
Reference : | Cheng, Z., Sun, L., He, J., Gong, W.(2007) Crystal structure of human {micro}-crystallin complexed with NADPHProtein Sci.16: 329-335 |
Gene Name : | CRYM |
Synonyms : | DFNA40; THBP; NADP-regulated thyroid-hormone binding protein; OTTHUMP00000115878; dfna40; crystallin mu |
UniProt ID : | Q14894 |
Gene ID : | 1428 |
Chromosome Location : | 16p13.11-p12.3 |
Function : | NADP or NADPH binding; catalytic activity; thyroid hormone binding; transcription corepressor activity |
Products Types
◆ Recombinant Protein | ||
Crym-2335M | Recombinant Mouse Crym Protein, Myc/DDK-tagged | +Inquiry |
CRYM-2006M | Recombinant Mouse CRYM Protein, His (Fc)-Avi-tagged | +Inquiry |
CRYM-872R | Recombinant Rhesus Macaque CRYM Protein, His (Fc)-Avi-tagged | +Inquiry |
CRYM-1281R | Recombinant Rat CRYM Protein, His (Fc)-Avi-tagged | +Inquiry |
CRYM-1945H | Recombinant Human CRYM Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
CRYM-7254HCL | Recombinant Human CRYM 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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