The neurotrophin-3 and p75NTR symmetrical
| Cat.No. : | CBCRY18 |
- Specification
- Gene Information
- Related Products
| Cat. No. : | CBCRY18 |
| Background : | Neurotrophins (NTs) are important regulators for the survival, differentiation and maintenance of different peripheral and central neurons. NTs bind to two distinct classes of glycosylated receptor: the p75 neurotrophin receptor (p75(NTR)) and tyrosine kinase receptors (Trks). Whereas p75(NTR) binds to all NTs, the Trk subtypes are specific for each NT. |
| Protein Classification : | signaling protein |
| Structure Weight : | 63861.22 |
| Polymer : | 1 |
| Molecule : | Neurotrophin-3 |
| Chain Length : | 119 amino acids |
| PDB ID : | 3BUK |
| MMDB ID : | 65479 |
| Source : | E.coli |
| Method : | X-Ray Diffraction |
| Resolution : | 2.6Å |
| Ligand Chemical Component : | N-Acetyl-D-Glucosamine |
| Reference : | Gong, Y., Cao, P., Yu, H.J., Jiang, T.(2008) Crystal structure of the neurotrophin-3 and p75NTR symmetrical complex.Nature454: 789-793 |
| Gene Name : | NTF3 |
| Synonyms : | HDNF; MGC129711; NGF-2; NGF2; NT3; Nerve growth factor 2; neurotrophic factor; neurotrophin 3 |
| UniProt ID : | P20783 |
| Chromosome Location : | 12p13 |
| Function : | growth factor activity; nerve growth factor binding; neurotrophin receptor binding |
| Gene ID : | 4804 |
Related Gene
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