Catalog # or name ...
Neurotrophins (NTs) are important regulators for the survival, differentiation and maintenance of different peripheral and central neurons. NTs bind to two distinct classes of glycosylated receptor: the p75 neurotrophin receptor (p75(NTR)) and tyrosine kinase receptors (Trks). Whereas p75(NTR) binds to all NTs, the Trk subtypes are specific for each NT.
119 amino acids
Tumor necrosis factor receptor superfamily member 16
167 amino acids
Ligand Chemical Component
HDNF; MGC129711; NGF-2; NGF2; NT3; Nerve growth factor 2; neurotrophic factor; neurotrophin 3
growth factor activity; nerve growth factor binding; neurotrophin receptor binding
CD271; Gp80-LNGFR; TNFRSF16; p75(NTR); p75NTR; low affinity nerve growth factor receptor; low-affinity nerve growth factor receptor; nerve growth factor receptor; CD271 antigen; NGF receptor; nerve growth factor receptor
death receptor activity; nerve growth factor binding; protein binding
Gong, Y., Cao, P., Yu, H.J., Jiang, T. (2008) Crystal structure of the neurotrophin-3 and p75NTR symmetrical complex. Nature 454: 789-793
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