Active Recombinant Human Superoxide Dismutase 1, Soluble, His-tagged
Cat.No. : | SOD1-326H |
- Specification
- Gene Information
- Related Products
Cat. No. : | SOD1-326H |
Description : | Cu/Zn Superoxide Dismutase (Cu/Zn SOD) catalyzes the dismutation of superoxide radicals to molecular oxygen. It has been implicated in cellular aging due to its reduced activity in aging cells. Cu/Zn SOD plays a protective role in the pathogenesis of selective neuronal injury after brief ischemia and reduces the degree of necrotic and DNA fragmented neuronal death following global ischemia. Mutant forms of Cu/Zn SOD have been linked to neurodegenerative diseases such as amyotrophic lateral sclerosis. |
Source : | E. coli. |
Usage : | For in vitro use only. |
Form : | Liquid. Supplied in 50 mM sodium citrate buffer pH 5.5, 1 mM DTT, 200 μM ZnSO4, and 200 μM CuSO4. |
Activity : | > 2.000 units/mg (One unit is defined as the amount of enzyme that will double the rate of autoxidation of 5, 6, 6a, 11b-tetrahydro- 3, 9,10-trihydroxybenzo-[c]- fluorene per minute at 37°C, pH 8.8). |
Purity : | > 90% by SDS-PAGE. |
Storage : | Quality guaranteed for 12 months, Store at -80°C. Avoid freeze / thaw cycles. |
Publication : |
Superoxide Dismutase 1 Regulation of CXCR4-Mediated Signaling in Prostate Cancer Cells is Dependent on Cellular Oxidative State (2015)
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Gene Name : | SOD1 superoxide dismutase 1, soluble [ Homo sapiens ] |
Synonyms : | SOD1; superoxide dismutase 1, soluble; ALS; SOD; ALS1; IPOA; homodimer; SOD, soluble; indophenoloxidase A; Cu/Zn superoxide dismutase; superoxide dismutase, cystolic; EC 1.15.1.1; Superoxide dismutase [Cu-Zn] |
Gene ID : | 6647 |
mRNA Refseq : | NM_000454 |
Protein Refseq : | NP_000445 |
MIM : | 147450 |
UniProt ID : | P00441 |
Chromosome Location : | 21q22.11 |
Pathway : | Amyotrophic lateral sclerosis (ALS); Huntington"s disease; Prion diseases; Hemostasis |
Function : | antioxidant activity; chaperone binding; copper ion binding; metal ion binding; protein homodimerization activity; protein phosphatase 2B binding; superoxide dismutase activity; zinc ion binding |
Products Types
◆ Native Protein | ||
SOD1-102B | Active Native Bovine SOD, modified | +Inquiry |
SOD1-101B | Active Native Bovine SOD | +Inquiry |
CED026 | Active Bovine Superoxide Dismutase (SOD), High Purity >95% | +Inquiry |
◆ Lysates | ||
SOD1-1576HCL | Recombinant Human SOD1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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