Enolase-phosphatase E1
Cat.No. : | CBCRY26 |
- Specification
- Gene Information
- Related Products
Cat. No. : | CBCRY26 |
Background : | Enolase-phosphatase E1 (MASA) is a bifunctional enzyme in the ubiquitous methionine salvage pathway that catalyzes the continuous reactions of 2,3-diketo-5-methylthio-1-phosphopentane to yield the aci-reductone metabolite using Mg2+ as cofactor. In this study, we have determined the crystal structure of MASA and its complex with a substrate analog to 1.7A resolution by multi-wavelength anomalous diffraction and molecular replacement techniques, respectively. |
Protein Classification : | Hydrolase |
Structure Weight : | 29316.11 Da |
Polymer : | 1 |
Molecule : | E-1 Enzyme |
Chain Length : | 285 amino acids |
PDB ID : | 1ZS9 |
MMDB ID : | 33918 |
Source : | E.coli |
Method : | X-Ray Diffraction |
Resolution : | 1.7Å |
Ligand Chemical Component : | Selenomethionine |
Reference : | Wang, H., Pang, H., Bartlam, M., Rao, Z. (2005) Crystal Structure of Human E1 Enzyme and its Complex with a Substrate Analog Reveals the Mechanism of its Phosphatase/Enolase J.Mol.Biol. 348: 917-926 |
Gene Name : | ENOPH1 |
Synonyms : | DKFZp586M0524; E1; FLJ12594; MASA; MST145; E-1 enzyme; Enolase-phosphatase E1; MSTP145 protein; acireductone synthase; EC 3.1.3.77; 2,3-diketo-5-methylthio-1-phosphopentane phosphatase; MASA homolog |
UniProt ID : | Q9UHY7 |
Gene ID : | 58478 |
Chromosome Location : | 4q21.22 |
Function : | magnesium ion binding; phosphor-glycolate phosphatase activity; acireductone synthase activity; metal ion binding; catalytic activity |
Products Types
◆ Recombinant Protein | ||
ENOPH1-2854H | Recombinant Human ENOPH1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Enoph1-2828M | Recombinant Mouse Enoph1 Protein, Myc/DDK-tagged | +Inquiry |
ENOPH1-1758R | Recombinant Rat ENOPH1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ENOPH1-2795M | Recombinant Mouse ENOPH1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ENOPH1-3457H | Recombinant Human ENOPH1 protein, His-tagged | +Inquiry |
◆ Lysates | ||
ENOPH1-6597HCL | Recombinant Human ENOPH1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket